Mdm2-binding protein (MTBP)

Inhibits cell migration in vitro and inhibits the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells.

Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This boosts MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.