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- Table of Contents
Facts about 39S ribosomal protein L49, mitochondrial.
Human | |
---|---|
Gene Name: | MRPL49 |
Uniprot: | Q13405 |
Entrez: | 740 |
Belongs to: |
---|
mitochondrion-specific ribosomal protein mL49 family |
C11orf4; L49mt39S ribosomal protein L49, mitochondrial; mitochondrial ribosomal protein L49; MRP-L49; Neighbor of FAU; next to FAU; NOF1chromosome 11 open reading frame 4; NOFMGC10656; Protein NOF1
Mass (kDA):
19.198 kDA
Human | |
---|---|
Location: | 11q13.1 |
Sequence: | 11; NC_000011.10 (65122183..65127371) |
Ubiquitous.
Mitochondrion.
This article focuses on Boster Bio's Anti-MRPL49 marker. We also discuss their history and the high affinity primary antibodies they make. We also discuss Steven Boster, his career in biotechnology. This information can be used by researchers and scientists around the globe. These are the best uses for the Boster Bio Anti-MRPL49 Symbol.
Boster Bio Anti MRPL49 Markers are a good choice if you are looking to perform an IHC test. This monoclonal antibody has been proven to work on positive and negative samples. It is also non-hazardous. If you do not wish to order the BSA, you can order it without it. To reduce cost, you can purchase a blocking peptide for the antibody.
Known for its high-affinity antibodies, Boster Bio produces a variety of ELISA kits and reagents. Boster lab products have been tested for ELISA/WB use. The product range includes products in neuroscience, veterinary medicine, immunology, and more. Boster guarantees that the antibody will perform as promised.
Monoclonal antibody are very cost-effective and can recognize multiple epitopes in a single antigen. They are stable in a wide range of pH levels and salt concentrations. Monoclonal antibodies are also made from a DNA sequence, which allows for custom tailoring of the molecule to a specific epitope. Boster Bio's high-affinity primary antibodies use the MRPL49 marker for maximum specificity.
While high affinity is desirable for antibody research, it can also make it difficult to separate the antibody and antigen. High affinity antibodies may require harsher or denaturing methods to separate them. A high-affinity antibody can be extremely useful in some applications. It can detect, purify and measure the antigen that is of interest and can be invaluable for many research projects.
Boster Bio's high-affinity antibodies use the MRPL49 marker in the development of their high-affinity primary antibodies. MRPL49 is where the antigen will be detected. This epitope can only be recognized by the antibody if the antigen has been fixed. Short incubation times can lead to signal attenuation.
Boster Bio high affinity primary antibodies not only use the MRPL49 marker but also contain the MRPL49 epitope. This allows them to recognize different epitopes within one protein immunogen. But, two antibodies may be used together and could have different binding patterns, which could result in a nonspecific signal.
Despite their high affinity, some studies show that their concentrations decrease upon affinity purification. This is because most high-affinity antibody do not elute well in affinity columns and their molecular "shape is" similar to the immunegen. False-positive results are more likely to occur if the antibody concentration is higher. To avoid false positive results, it is important to first block the staining with high-affinity antibodies.
Steve Boster created the first product for immunohistochemistry (IHC). His products contained hundreds of primary antibody and his company became the largest Chinese catalog antibody company by the end of the nineties. PicoKine(tm), a proprietary ELISA platform developed by him, delivers high-sensitivity ELISA Kits. A history of his company is described here.
Steve Boster, a Joliet native, was born June 6, 1931 and passed away in Madison, WI on June 6, 2022. He was a Vietnam veteran, a member of Concordia Hall of Staunton, as well as a long-time manager of retail sales. His surviving family members include his daughters Natosha Peck and Crystal Boster, 6 Grandchildren, and 4 Brothers, Jack Boster and Sandra Blanton. His sister Tammy and niece Kimberly reside in Herrin IL, as does his brother Jonathan.
PMID: 8786148 by Kas K., et al. Isolation, cDNA, and genomic structure of a conserved gene (NOF) at chromosome 11q13 next to FAU and oriented in the opposite transcriptional orientation.
PMID: 11551941 by Koc E.C., et al. The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.