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- Table of Contents
Facts about Melanocortin-2 receptor accessory protein 2.
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Human | |
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Gene Name: | MRAP2 |
Uniprot: | Q96G30 |
Entrez: | 112609 |
Belongs to: |
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MRAP family |
Melanocortin-2 receptor accessory protein 2
Mass (kDA):
23.548 kDA
Human | |
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Location: | 6q14.2 |
Sequence: | 6; NC_000006.12 (84032621..84146278) |
Expressed in the adrenal gland and brain. Not expressed in other tissues.
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. The formation of antiparallel homo- and heterodimers suggest that N- and C-terminus can both localize in the cytoplasmic and extracellular parts, depending on the context.
PMID: 19329486 by Chan L.F., et al. MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family.
PMID: 20371771 by Sebag J.A., et al. Regulation of G protein-coupled receptor signaling: specific dominant-negative effects of melanocortin 2 receptor accessory protein 2.