MPRIP Antibodies

AND MPRIP ELISA kits, MPRIP Proteins

Many biological assays use antibodies to detect MPRIP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MPRIP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MPRIP antibodies...

We validate the specificity of these antibodies to MPRIP by testing them on tissues known to express MPRIP positively and negatively. Browse below to find the MPRIP antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MPRIP Infographic by Boster Bio

All MPRIP Products

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Specificity

Applications

Price

Anti-M-RIP MPRIP Antibody

5 Q&As

Human, Mouse, Rat

$399
Cat # A05678
100μl

MPRIP (NM_201274) Human Over-expression Lysate

Human

$960
Cat # LS023164
100 µg

MPRIP Overview

Facts about Myosin phosphatase Rho-interacting protein.

MPRIP 3D structure. Source: alphafold

Myosin phosphatase Rho-interacting protein (MPRIP)

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1.

Depletion leads to an increased variety of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F- actin-binding area leads to disassembly of stress fibers in neuronal cells.

Gene Information

Human
Gene Name:	MPRIP
Uniprot:	Q6WCQ1
Entrez:	23164

Family

Belongs to:

No superfamily

Alternative Names

KIAA0864Rho interacting protein 3; MRIPP116RIP; myosin phosphatase Rho interacting protein; p116Ripmyosin phosphatase-Rho interacting protein; RHOIP3myosin phosphatase Rho-interacting protein; RIP3M-RIPRho-interacting protein 3

Molecular Weight

Mass (kDA):
116.533 kDA

Genomic Context


Human

Location:	17p11.2
Sequence:	17; NC_000017.11 (17042455..17192648)

Subcellular Localizations

Cytoplasm, cytoskeleton. Colocalizes with F-actin.

Interacting Proteins

Ppp1r12a
YWHAZ

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MPRIP

References

PMID: 14506264 by Surks H.K., et al. Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA.

PMID: 15545284 by Koga Y., et al. p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA.