Mpp5 Antibodies

AND Mpp5 ELISA kits, Mpp5 Proteins

Many biological assays use antibodies to detect Mpp5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mpp5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mpp5 antibodies...

We validate the specificity of these antibodies to Mpp5 by testing them on tissues known to express Mpp5 positively and negatively. Browse below to find the Mpp5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Mpp5 Infographic by Boster Bio

All Mpp5 Products

Product

Figures

Specificity

Applications

Price

Anti-PALS1 Mouse Monoclonal Antibody [Clone ID: OTI2D3]

Dog, Human, Mouse, Rat

Flow Cytometry, WB

$523
Cat # M05311
100 µl

PALS1 (NM_022474) Human Over-expression Lysate

Human

$628
Cat # LS064398
100 µg

Mpp5 Overview

Facts about MAGUK p55 subfamily member 5.

MAGUK p55 subfamily member 5 (Mpp5)

May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter.

Required for localization of EZR to the apical membrane of parietal cells and might play a role in the dynamic remodeling of the apical cytoskeleton. .

Gene Information

Mouse
Gene Name:	Mpp5
Uniprot:	Q9JLB2
Entrez:	56217

Family

Belongs to:

MAGUK family

Alternative Names

MAGUK p55 subfamily member 5; membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); MPP5; PALS1; PALS1FLJ12615; Stardust

Molecular Weight

Mass (kDA):
77.229 kDA

Genomic Context


Mouse

Location:	12\|12 C3
Sequence:	12;

Tissue Specificity

Expressed in retina, lung, kidney, and heart. In the brain, expressed in the dentate gyrus of hippocampus, striatum and cerebellum (at protein level). Expressed in placenta, kidney, brain, heart, skeletal muscles, lung, pancreas and liver.

Diseases

Tissue Adhesions
Amaurosis
Neoplasms
Leber Congenital Amaurosis
Retinitis Pigmentosa
Retinal Diseases
Malignant Neoplasms
Retinal Degeneration
Retinal Dystrophies
Malignant Neoplasm Of Breast
Carcinoma
Dystrophy

Neurofibromatosis 2
Disorder Of Eye
Hyperplasia
Neoplasm Metastasis
Melanoma
Neoplasm Invasiveness
Lymphoma

Pathways

Localization
Cell-cell Adhesion
Cell Proliferation
Cell Adhesion
Cell Division
Cell Death
Transport
Heart Morphogenesis
Cell Growth
Secretion
Cell Activation
Cell Migration
Programmed Cell Death

Fertilization
Brain Development
Immune Response
Neurogenesis
Adaptive Immune Response
Nuclear Export
Asymmetric Cell Division

PTMs

Palmitoylation
Phosphorylation

Cleavage
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mpp5

References

PMID: 10753959 by Kamberov E., et al. Molecular cloning and characterization of Pals, proteins associated with mLin-7.

PMID: 11927608 by Roh M.H., et al. The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost.