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- Table of Contents
Facts about 2-acylglycerol O-acyltransferase 3.
Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.
Human | |
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Gene Name: | MOGAT3 |
Uniprot: | Q86VF5 |
Entrez: | 346606 |
Belongs to: |
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diacylglycerol acyltransferase family |
acyl coenzyme A:monoacylglycerol acyltransferase 3; Acyl-CoA:monoacylglycerol acyltransferase 3; DC72-acylglycerol O-acyltransferase 3; DGAT2L7MGC119203; Diacylglycerol acyltransferase 2-like protein 7; Diacylglycerol O-acyltransferase candidate 7; EC 2.3.1.20; EC 2.3.1.22; MGAT3; MGC119204; monoacylglycerol O-acyltransferase 3hDC7
Mass (kDA):
38.73 kDA
Human | |
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Location: | 7q22.1 |
Sequence: | 7; NC_000007.14 (101192886..101201131, complement) |
Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region.
PMID: 12618427 by Cheng D., et al. Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption.
PMID: 27184406 by Brandt C., et al. Biochemical characterization of human acyl coenzyme A: 2- monoacylglycerol acyltransferase-3 (MGAT3).