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- Table of Contents
Facts about 2-acylglycerol O-acyltransferase 2.
Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.
Human | |
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Gene Name: | MOGAT2 |
Uniprot: | Q3SYC2 |
Entrez: | 80168 |
Belongs to: |
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diacylglycerol acyltransferase family |
acyl CoA:monoacylglycerol acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; DC5; DGAT2L5MGC119183; Diacylglycerol acyltransferase 2-like protein 5; Diacylglycerol O-acyltransferase candidate 5; EC 2.3.1; EC 2.3.1.22; FLJ22644; hDC5; hMGAT2; MGAT2MGC119184; MGC119185; monoacylglycerol O-acyltransferase 22-acylglycerol O-acyltransferase 2
Mass (kDA):
38.196 kDA
Human | |
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Location: | 11q13.5 |
Sequence: | 11; NC_000011.10 (75717819..75732953) |
Highly expressed in liver, small intestine, colon, stomach and kidney.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region.
PMID: 12621063 by Yen C.-L.E., et al. MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine.
PMID: 12824082 by Lockwood J.F., et al. Human intestinal monoacylglycerol acyltransferase: differential features in tissue expression and activity.