MMP14 Antibodies

AND MMP14 ELISA kits, MMP14 Proteins

Many biological assays use antibodies to detect MMP14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MMP14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MMP14 antibodies...

We validate the specificity of these antibodies to MMP14 by testing them on tissues known to express MMP14 positively and negatively. Browse below to find the MMP14 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: MMP17

MMP14 Infographic by Boster Bio

All MMP14 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Matrix metalloproteinase-14 MMP14 Antibody Picoband®

9 Citations 16 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PA2147
100 μg/vial

Anti-MMP14 Antibody Picoband®

9 Citations 15 Q&As

Human

$370
Cat # PB9283
100 μg/vial

Anti-MMP14/Mt1 Mmp Rabbit Monoclonal Antibody

4 Citations 16 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M00656
100 μl

MMP-14 Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1376
1 kit, containing one 96-well plate and all necessary reagents

Anti-Cleaved-MMP-14 (Y112) Antibody

Human, Mouse, Rat

$405
Cat # A00656Y112
100ul

Anti-MMP14 Antibody (N-term)

Human, Mouse, Rat

Flow Cytometry, IHC-P, WB

$299
Cat # A00656
80 µl

MMP14 (NM_004995) Human Over-expression Lysate

Human

$628
Cat # LS004323
100 µg

MMP14 Overview

Facts about Matrix metalloproteinase-14.

MMP14 3D structure. Source: alphafold

Matrix metalloproteinase-14 (MMP14)

Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A.

Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484).

Gene Information

Human
Gene Name:	MMP14
Uniprot:	P50281
Entrez:	4323

Family

Belongs to:

peptidase M10A family

Alternative Names

EC 3.4.24; EC 3.4.24.80; matrix metallopeptidase 14 (membrane-inserted); matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase-14; membrane type 1 metalloprotease; Membrane-type matrix metalloproteinase 1; Membrane-type-1 matrix metalloproteinase; MMP14; MMP-14; MMP-X1; MT1MMP; MT1-MMP; MT1-MMPMTMMP1; MT-MMP 1; MT-MMP1

Molecular Weight

Mass (kDA):
65.894 kDA

Genomic Context


Human

Location:	14q11.2
Sequence:	14; NC_000014.9 (22836585..22847758)

Tissue Specificity

Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors.

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.

Diseases

Neoplasms
Malignant Neoplasms
Cell Invasion
Neoplasm Metastasis
Neoplasm Invasiveness
Carcinoma
Tumor Angiogenesis
Mammary Neoplasms
Tissue Adhesions
Malignant Neoplasm Of Breast
Pathologic Neovascularization
Malignant Paraganglionic Neoplasm

Tumor Progression
Inflammation
Melanoma
Cell Transformation, Neoplastic
Lung Neoplasms
Adenocarcinoma
Malignant Squamous Cell Neoplasm

Interacting Proteins

ADI1
BCAR1
CCDC155
FGFR4
FURIN

Gorasp2
LIMK1
LUM
TIMP2

Pathways

Cell Migration
Angiogenesis
Proteolysis
Localization
Cell Adhesion
Cell Proliferation
Pathogenesis
Cell Growth
Cell Motility
Tissue Remodeling
Secretion
Rna Interference
Regeneration

Endocytosis
Wound Healing
Tube Formation
Bone Resorption
Lung Development
Gene Silencing
Gastrulation

PTMs

Cleavage
Phosphorylation
Methylation
Demethylation
Biotinylation
Glycosylation

Dephosphorylation
Ubiquitination
Reduction
Deacetylation
Acetylation
Palmitoylation

Deglycosylation

Research Areas

Cancer
Extracellular Matrix

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MMP14

References

PMID: 8015608 by Sato H., et al. A matrix metalloproteinase expressed on the surface of invasive tumour cells.

PMID: 7721107 by Takino T., et al. Cloning of a human gene potentially encoding a novel matrix metalloproteinase having a C-terminal transmembrane domain.

10 Publications of Boster MMP14 Antibodies & ELISA Kits

PubMed ID: 29393353, Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK...
PubMed ID: 27453531, The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-?1 p...
PubMed ID: 27882817, Yan Li, Lin Li, Ou Zeng, Jun Mao Liu & Jun Yang H2S improves renal fibrosis in S...
PubMed ID: 24628713, Zhang Jt, Sun W, Zhang Wz, Ge Cy, Liu Zy, Zhao Zm, Lu Xs, Fan Yz. Bmc Cancer. 20...
PubMed ID: 24765144, Zhou H, Wu A, Fu W, Lv Z, Zhang Z. Oncol Lett. 2014 May;7(5):1395-1400. Epub 201...
PubMed ID: 20579139, Dong Q, Yu D, Yang Cm, Jiang B, Zhang H. Int J Exp Pathol. 2010 Aug;91(4):368-73...
PubMed ID: 25673203, Shi Ch, Wang Ws, Zhang Zd, Li Cj, Guo Fj, Li F, Chen Am. J Huazhong Univ Sci Tec...
PubMed ID: 24573354, Xiao H, Li H, Yu G, Xiao W, Hu J, Tang K, Zeng J, He W, Zeng G, Ye Z, Xu H. Onco...
PubMed ID: 23058919, Jin F, Jiang S, Yang D, Zhang X, Yang Y, Zhang Y, Li K, Yang Y, Ma S. Biochem Bi...
PubMed ID: 23795739, Jiang S, Jin F, Li D, Zhang X, Yang Y, Yang D, Li K, Yang Y, Ma S. High Alt Med ...

*More publications can be found for each product on its corresponding product page