MMP17 Antibodies

AND MMP17 ELISA kits, MMP17 Proteins

Many biological assays use antibodies to detect MMP17, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MMP17 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MMP17 antibodies...

We validate the specificity of these antibodies to MMP17 by testing them on tissues known to express MMP17 positively and negatively. Browse below to find the MMP17 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MMP17 Infographic by Boster Bio

All MMP17 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Cleaved-MMP-17 (Q129) Antibody

7 Q&As

Human

ELISA, WB

$399
Cat # A08090
100μl

Anti-MMP-17 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A08090-1
100ul

Anti-MMP17 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M08090-1
100 μl/vial

MMP17 (NM_016155) Human Over-expression Lysate

Human

$628
Cat # LS004326
100 µg

MMP17 Overview

Facts about Matrix metalloproteinase-17.

MMP17 3D structure. Source: alphafold

Matrix metalloproteinase-17 (MMP17)

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha.

May also be involved in tumoral procedure. Cleaves pro-TNF-alpha at the'74-Ala-.

Gene Information

Human
Gene Name:	MMP17
Uniprot:	Q9ULZ9
Entrez:	4326

Family

Belongs to:

peptidase M10A family

Alternative Names

matrix metallopeptidase 17 (membrane-inserted); matrix metalloproteinase 17 (membrane-inserted); matrix metalloproteinase-17; membrane-type matrix metalloproteinase 4; membrane-type-4 matrix metalloproteinase; MMP17; MMP-17; MT4MMP; MT4-MMP; MT-MMP 4; MTMMP4

Molecular Weight

Mass (kDA):
66.653 kDA

Genomic Context


Human

Location:	12q24.33
Sequence:	12; NC_000012.12 (131828393..131851771)

Tissue Specificity

Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types.

Subcellular Localizations

[Isoform Long]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix.

Diseases

Neoplasms
Carcinoma
Malignant Neoplasms
Cell Invasion
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Mammary Neoplasms
Malignant Paraganglionic Neoplasm
Inflammation
Tumor Progression
Degenerative Polyarthritis
Tissue Adhesions

Aneurysm
Neoplasm Metastasis
Adenoma
Metaplasia
Polyps
Mitochondrial Diseases
Malignant Tumor Of Colon

Pathways

Localization
Transport
Cell Migration
Translation
Eosinophil Migration
Tissue Remodeling
Proteolysis
Angiogenesis

Ovulation
Oxidative Phosphorylation

PTMs

Cleavage
Biotinylation

Glycosylation
Gpi Anchoring

Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MMP17

References

PMID: 10471807 by Kajita M., et al. Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts.

PMID: 8640782 by Puente X.S., et al. Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma.