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- Table of Contents
Facts about Membrane metallo-endopeptidase-like 1.
Shares the same substrate specificity with MME and cleaves peptides at precisely the identical amide bond. .
Mouse | |
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Gene Name: | Mmel1 |
Uniprot: | Q9JLI3 |
Entrez: | 27390 |
Belongs to: |
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peptidase M13 family |
EC 3.4.24; EC 3.4.24.11; MELL1; membrane metallo-endopeptidase-like 1; Membrane metallo-endopeptidase-like 2MGC119455; MGC119454; MMEL1; MMEL2; NEP2; NEP2(m); NEPIIMGC119456; Neprilysin II; Neprilysin2; Neprilysin-2; NL2; NL2NL1; SEP; soluble secreted endopeptidase; zinc metallopeptidase
Mass (kDA):
88.7 kDA
Mouse | |
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Location: | 4|4 E2 |
Sequence: | 4; |
Highly expressed in testis. Also expressed in ovary. Weakly or not expressed in brain, lung, heart, liver, kidney, adrenal gland and intestine.
PMID: 10542292 by Ikeda K., et al. Molecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides.
PMID: 10749671 by Ghaddar G., et al. Molecular cloning and biochemical characterization of a new mouse testis soluble zinc-metallopeptidase of the neprilysin family.