MLXIPL Antibodies

AND MLXIPL ELISA kits, MLXIPL Proteins

Many biological assays use antibodies to detect MLXIPL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MLXIPL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MLXIPL antibodies...

We validate the specificity of these antibodies to MLXIPL by testing them on tissues known to express MLXIPL positively and negatively. Browse below to find the MLXIPL antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MLXIPL Infographic by Boster Bio

All MLXIPL Products

Product

Figures

Specificity

Applications

Price

Anti-MLXIPL Antibody

Human, Mouse

$405
Cat # A03145
100ul

CHREBP (MLXIPL) (NM_032951) Human Over-expression Lysate

Human

$960
Cat # LS051085
100 µg

MLXIPL Overview

Facts about Carbohydrate-responsive element-binding protein.

MLXIPL 3D structure. Source: alphafold

Carbohydrate-responsive element-binding protein (MLXIPL)

Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity).

. .

Gene Information

Human
Gene Name:	MLXIPL
Uniprot:	Q9NP71
Entrez:	51085

Family

Belongs to:

No superfamily

Alternative Names

BHLHD14; CHREBPcarbohydrate-responsive element-binding protein; Class D basic helix-loop-helix protein 14; MIOWS basic-helix-loop-helix leucine zipper protein; MLX interacting protein-like; MLX interactor; MLX-interacting protein-like; MONDOBWilliams-Beuren syndrome chromosomal region 14 protein; WBSCR14Williams-Beuren syndrome chromosome region 14 protein 1; Williams Beuren syndrome chromosome region 14; Williams-Beuren syndrome chromosome region 14 protein 2; WS-bHLHbHLHd14carbohydrate response element binding protein

Molecular Weight

Mass (kDA):
93.073 kDA

Genomic Context


Human

Location:	7q11.23
Sequence:	7; NC_000007.14 (73593201..73624522, complement)

Tissue Specificity

Expressed in liver, heart, kidney, cerebellum and intestinal tissues.

Subcellular Localizations

Nucleus.

Diseases

Obesity
Diabetes Mellitus
Fatty Liver
Diabetes Mellitus, Non-insulin-dependent
Insulin Resistance
Cardiovascular Diseases
Coronary Artery Disease
Malignant Neoplasms
Steatohepatitis
Steatosis
Liver Diseases
Williams Syndrome
Metabolic Syndrome X

Insulin Sensitivity
Dyslipidemias
Neoplasms
Impaired Glucose Tolerance
Liver Carcinoma
Haploinsufficiency
Dysequilibrium Syndrome

Pathways

Localization
Glycolysis
Nuclear Export
Oxidative Phosphorylation
Transport
Gluconeogenesis
Cell Cycle
Insulin Secretion
Pathogenesis
Secretion
Cholesterol Esterification
Cell Cycle Arrest
Inflammatory Response

Glucose Homeostasis
Cell Motility
Cognition
Nuclear Import
Cell Proliferation
Pancreas Development
Parturition

PTMs

Phosphorylation
Dephosphorylation

Glycosylation
Cleavage

Oxidation

Research Areas

Cancer
DNA replication, Transcription, Translation and Splicing
Lipid and Metabolism
Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MLXIPL

References

PMID: 10780788 by de Luis O., et al. WBSCR14, a putative transcription factor gene deleted in Williams- Beuren syndrome: complete characterisation of the human gene and the mouse ortholog.

PMID: 11230181 by Cairo S., et al. WBSCR14, a gene mapping to the Williams-Beuren syndrome deleted region, is a new member of the Mlx transcription factor network.