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- Table of Contents
Facts about Muskelin.
Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1 (PubMed:18710924). .
Human | |
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Gene Name: | MKLN1 |
Uniprot: | Q9UL63 |
Entrez: | 4289 |
Belongs to: |
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No superfamily |
FLJ11162; muskelin 1, intracellular mediator containing kelch motifs; muskelin; TWA2
Mass (kDA):
84.768 kDA
Human | |
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Location: | 7q32.3 |
Sequence: | 7; NC_000007.14 (131110094..131496637) |
Cytoplasm. Cytoplasm, cytosol. Nucleus, nucleoplasm. Cell projection, ruffle. Cytoplasm, cell cortex. Cell junction, synapse. Cell junction, synapse, postsynapse. Colocalizes with GABRA1 at synapses and in postsynaptic regions. Colocalizes with actin fibers in the cell cortex.
PMID: 10640805 by Adams J.C., et al. cDNA cloning of human muskelin and localisation of the muskelin (MKLN1) gene to human chromosome 7q32 and mouse chromosome 6 B1/B2 by physical mapping and FISH.
PMID: 12559565 by Umeda M., et al. A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM.