MKI67 Antibodies

AND MKI67 ELISA kits, MKI67 Proteins

Many biological assays use antibodies to detect MKI67, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MKI67 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MKI67 antibodies...

We validate the specificity of these antibodies to MKI67 by testing them on tissues known to express MKI67 positively and negatively. Browse below to find the MKI67 antibody that suites your experiment. We have 14 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: MKLN1

MKI67 Infographic by Boster Bio

All MKI67 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Ki67/MKI67 Antibody Picoband®

48 Citations

Human

$370
Cat # PA1918
100 μg/vial

Anti-Ki67/MKI67 Antibody Picoband®

62 Citations 3 Q&As

Human

IF, IHC, ICC, WB

$370
Cat # PB9026
100 μg/vial

Anti-Ki67 MKI67 Rabbit Monoclonal Antibody

23 Citations 7 Q&As

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M00254
100 μl

Human Ki67 ELISA Kit PicoKine®

1 Citations 7 Q&As

Human

ELISA

$499
Cat # EK1759
96 wells/kit, with removable strips.

Anti-Human Ki-67 Monoclonal Antibody

13 Citations

Human

IF, ICC, WB

$299
Cat # M00254-1
100ul

Anti-Human Ki-67 Monoclonal Antibody

11 Citations

Human

IF, WB

$299
Cat # M00254-2
100ul

Anti-Human Ki67 Antibody

16 Citations

Human, Mouse, Rat

IF, IHC, ICC, WB

$299
Cat # M00254-3
100ul

Anti-Ki-67 MKI67 Antibody

12 Citations

Human, Mouse, Rat

IF, IHC, ICC, WB

$299
Cat # M00254-4
100ul

Anti-KI67 MKI67 Rabbit Monoclonal Antibody, Clone#RM360

11 Citations

Human

IHC, WB

$431
Cat # M00254-5
100uL

Anti-Ki 67 MKI67 Monoclonal Antibody

4 Citations

Human, Mouse, Rat

IHC

$380
Cat # M00254-7
100ul

Anti-Ki67/Mki67 Antibody

18 Citations

Human, Mouse, Rat

ELISA, IHC

$370
Cat # A00254
100 μg/vial

Anti-Ki67 Antibody (monoclonal, 5E12)

1 Citations

Human

Flow Cytometry, IF, IHC, ICC

$370
Cat # M00254-8
100 μg/vial

Anti-Ki67 Antibody Picoband® (monoclonal, 5C7)

9 Citations

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M00254-9
100 μg/vial

Anti-Ki67/MKI67 Antibody

Human

ELISA, IHC

$370
Cat # A00254-1
100 μg/vial

MKI67 Overview

Facts about Proliferation marker protein Ki-67.

Proliferation marker protein Ki-67 (MKI67)

Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a significant portion of the chromosome surface (PubMed:27362226).

Prevents chromosomes from collapsing to a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551).

Gene Information

Human
Gene Name:	MKI67
Uniprot:	P46013
Entrez:	4288

Family

Belongs to:

No superfamily

Alternative Names

antigen identified by monoclonal Ki-67; Antigen Ki67; antigen KI-67; antiKi67; Ki67 ihc; Ki-67 ihc; Ki67 mouse; Ki-67 mouse; Ki67 western blot; Ki-67 western blot; Ki67; Ki-67; KIA; Marker Of Proliferation Ki-67; MIB-; MIB-1; MKI67; PPP1R105; Proliferation Marker Protein Ki-67; proliferation-related Ki-67 antigen; Protein Phosphatase 1; Regulatory Subunit 105; TSG126

Molecular Weight

Mass (kDA):
358.694 kDA

Genomic Context


Human

Location:	10q26.2
Sequence:	10; NC_000010.11 (128096659..128126423, complement)

Subcellular Localizations

Chromosome. Nucleus. Nucleus, nucleolus. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the mitotic chromosome surface (PubMed:27362226). Associates with satellite DNA in G1 phase (PubMed:9510506). Binds tightly to chromatin in interphase, chromatin-binding decreases in mitosis when it associates with the surface of the condensed chromosomes (PubMed:15896774, PubMed:22002106). Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Breast
Carcinoma
Mammary Neoplasms
Hyperplasia
Prostatic Neoplasms
Tumor Angiogenesis
Malignant Neoplasm Of Prostate
Endometrial Polyp
Tissue Adhesions
Adenocarcinoma
Malignant Paraganglionic Neoplasm

Neoplasm Recurrence, Local
Neoplasm Metastasis
Neoplasm Invasiveness
Fibrosis
Cell Transformation, Neoplastic
Liver Carcinoma
Cell Invasion

Interacting Proteins

KIF15
NIFK

Pathways

Cell Proliferation
Cell Cycle
Neurogenesis
Pathogenesis
Angiogenesis
Mitosis
Cell Growth
Cell Division
Epithelial Cell Proliferation
Localization
Regeneration
Dedifferentiation
Senescence

Methylation
Cell Death
Secretion
Cell Differentiation
Dna Repair
Cell Development
Cell Adhesion

PTMs

Phosphorylation
Methylation

Cleavage
Ribosylation

Myristoylation

Research Areas

Breast Cancer
Cancer
Cell Biology
Cell Cycle and Replication
Cellular Markers

Chromatin Research
Mitotic Regulators
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MKI67

References

PMID: 8227122 by Schlueter C., et al. The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins.

PMID: 6339421 by Gerdes J., et al. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation.

95 Publications of Boster MKI67 Antibodies & ELISA Kits

PubMed ID: PMID:31966612, Clinical biocharacterization of immunophenotype in hepatocellular carcinoma pati...
PubMed ID: PMID:30210698, Identification and differentiation therapy strategy of pterygium in vitro
PubMed ID: 10.3892/ol.2021.12762, Antimicrobial peptide 17BIPHE2 inhibits the proliferation of lung cancer cells <...
PubMed ID: 10.3892/ol.2016.4690, Label-retaining assay enriches tumor-initiating cells in glioblastoma spheres cu...
PubMed ID: 10.3892/ol.2016.4380, Preclinical pharmacodynamic evaluation of antibiotic nitroxoline for anticancer ...
PubMed ID: 10.3892/ijmm.2021.5071, Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasio...
PubMed ID: 10.3748/wjg.v13.i48.6558, PlexinA1 expression in gastric carcinoma and its relationship with tumor angioge...
PubMed ID: 10.2485/jhtb.30.273, Elevated CREPT Expression Enhances the Progression of Salivary Gland Adenoid Cys...
PubMed ID: 10.1186/s13046-021-02120-4, Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune chec...
PubMed ID: 10.1186/s12935-021-01775-5, Regulator of cullins-1 (ROC1) negatively regulates the Gli2 regulator SUFU to ac...
PubMed ID: 10.1186/s12935-020-1150-1, Hsa_circ_0137008 suppresses the malignant phenotype in colorectal cancer by acti...
PubMed ID: 10.1186/1471-2407-9-315, Cripto-1 overexpression is involved in the tumorigenesis of nasopharyngeal carci...
PubMed ID: 10.1161/ATVBAHA.120.315525, Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Ce...
PubMed ID: 10.1158/1541-7786.MCR-12-0632, Balanced Tiam1-Rac1 and RhoA Drives Proliferation and Invasion of Pancreatic Can...
PubMed ID: 10.1111/j.1440-1797.2008.00939.x, R2: Identification of renal potential progenitor/stem cells that participate in ...
PubMed ID: 10.1111/apm.12427, Leukemia inhibitory factor promotes tumor growth and metastasis in human osteosa...
PubMed ID: 10.1093/carcin/bgr035, Low-level expression of let-7a in gastric cancer and its involvement in tumorige...
PubMed ID: 10.1088/1758-5090/8/4/045005, 3D bioprinted glioma stem cells for brain tumor model and applications of drug s...
PubMed ID: 10.1080/13880209.2021.1944224, Cryptotanshinone enhances the efficacy of Bcr-Abl tyrosine kinase inhibitors via...
PubMed ID: 10.1038/srep27559, Core-shell nanocarriers with high paclitaxel loading for passive and active targ...
PubMed ID: 10.1038/s41419-020-03064-x, PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal ca...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page