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Midnolin Antibodies
AND Midn ELISA kits, Midnolin Proteins
Many biological assays use antibodies to detect Midnolin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Midnolin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Midnolin antibodies...
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Midn Overview
Facts about Midnolin.
Midnolin (Midn)
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4 (PubMed:27326929). Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion (By similarity).
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Gene Information
| Mouse | |
|---|---|
| Gene Name: | Midn |
| Uniprot: | Q3TPJ7 |
| Entrez: | 59090 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DKFZp547M072; Midbrain nucleolar protein; midnolin
Molecular Weight
Mass (kDA):
49.192 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 10|10 C1 |
| Sequence: | 10; |
Tissue Specificity
Expressed at high levels in brain and liver with significantly lower levels in muscle.
Diseases
- Pain
- Ischemia
- Hemorrhage
- Warm Ischemia
- Nausea
- Haploinsufficiency
- Hypertensive Disease
- Malignant Neoplasms
- Peutz-jeghers Syndrome
Pathways
- Transport
- Glomerular Filtration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Midn
bosterbio.com/bosterbio-gene-info-cards/Midn
References
PMID: 10974535 by Tsukahara M., et al. Novel nucleolar protein, midnolin, is expressed in the mesencephalon during mouse development.
PMID: 24187134 by Hofmeister-Brix A., et al. Identification of the ubiquitin-like domain of midnolin as a new glucokinase interaction partner.