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- Table of Contents
Facts about RNA-binding protein MEX3B.
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Human | |
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Gene Name: | MEX3B |
Uniprot: | Q6ZN04 |
Entrez: | 84206 |
Belongs to: |
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No superfamily |
DKFZp434J0617; KIAA2009; mex-3 homolog B (C. elegans); ring finger and KH domain containing 3; RING finger and KH domain-containing protein 3; RING finger protein 195; RKHD3MGC117199; RNA-binding protein MEX3B; RNF195MEX-3B
Mass (kDA):
58.832 kDA
Human | |
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Location: | 15q25.2 |
Sequence: | 15; NC_000015.10 (82041778..82046018, complement) |
Highest levels found in fetal brain and testis. Detected in the adult intestinal epithelium, specifically in goblet cell at protein level.
Nucleus. Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule. Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3-3.
PMID: 17267406 by Buchet-Poyau K., et al. Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies.
PMID: 18779327 by Courchet J., et al. Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules.