DNA helicase MCM8 Antibodies

DNA helicase MCM8 (Mcm8)

Part of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays an integral role during gametogenesis. The MCM8- MCM9 complex probably functions as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is needed to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.

May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruitment CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.

Gene Information

Mouse
Gene Name:	Mcm8
Uniprot:	Q9CWV1
Entrez:	66634

Family

Belongs to:
MCM family

Alternative Names

C20orf154; chromosome 20 open reading frame 154; dJ967N21.5; DNA replication licensing factor MCM8; MCM8 minichromosome maintenance deficient 8; MGC119522; MGC119523; MGC12866; MGC4816; Minichromosome maintenance 8; minichromosome maintenance complex component 8; REC homolog; REC

Molecular Weight

Mass (kDA):
92.371 kDA

Genomic Context

Mouse
Location:	2|2 F2
Sequence:	2;

Diseases

• Premature Menopause
• Neoplasms
• Neuroblastoma
• Adenocarcinoma
• Fanconi Anemia
• Anemia
• Malignant Neoplasm Of Breast
• Colonic Neoplasms
• Genomic Instability
• Choriocarcinoma
• Infertility

• Bloom Syndrome
• Cardiovascular Diseases
• Malignant Neoplasms
• Adenocarcinoma Of Colon
• Ovarian Neoplasm
• Trematode Infections

Pathways

• Dna Replication
• Menopause
• S Phase
• Dna Replication Initiation
• Cell Cycle
• Menarche
• Cell Proliferation
• Meiotic Prophase I
• Dna Repair
• Gene Conversion

• Translesion Synthesis
• Prophase
• Meiosis
• Rna Interference

PTMs

• Phosphoprotein

Research Areas

• DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mcm8

Best Uses Of The MCM8 Marker

This article will outline the benefits of MCM8 Marker to researchers and discuss why Boster Bio’s primary antibodies can be trusted by the scientific community. The history of Steven Boster who is one of the founders Boster Bio will be revealed. You'll be able to choose the correct MCM8 Marker for you research after reading this article. It is clear that Boster Bio's first antibodies are a trusted choice by research professionals.

Benefits of using the MCM8 Marker

The MCM8 marker targets a protein called MCM8. (Minichromosome Maintenance 8). This 840-amino acid protein is abundant in many tissues, including the lung, pancreas and placenta. It is also involved in gametogenesis, homologous recombination and other important processes. MCM8 is vital for normal reproductive aging. It is also associated in immune cell penetration in melanoma.

Researchers trust Boster Bio's first antibodies

Boster Bio's extensive product line will provide the right solution for your needs. Their range of antibodies and reagents includes high-quality rabbit polyclonal antibodies and validated for IHC, WB, FC, ELISA, and WB. Boster Bio offers products in neuroscience, biology, and chemical. Each product comes with a guarantee of quality to ensure it works exactly the way it was described.

Boster is a world-renowned manufacturer of high-affinity primary antibodies. Their products have been used in research for more than 25 years, and have earned high-ranking scientific citations. Furthermore, Boster antibodies are validated on Western Blotting, Immunohistochemistry, and ELISA. The research community trusts them because of this.

Commercially available antibodies don't always have high quality. Berglund states that commercial antibodies have a high failure rate, which is a waste of money and time. Poorly performing antibodies cost US$800 million each year. Bad antibodies also cause biomedical research to lose 350 million dollars annually. Bad antibodies ultimately led to failed experiments.

Make sure you read the datasheets before purchasing a primary antibody. The datasheets should include the full name of your antibody, the vendor and lot number as well as details about how the antibody was created. References should include any positive controls and other data that will make the product reliable for your specific application. It is best to avoid using an antibody that lacks this information.

History of Steven Boster

Search his public records to see a full background on Steve Boster. This includes his current and previous addresses, phone numbers, and email addresses. You can also search his public records to see if there are any relatives. To learn more about Steve Boster, search his public records alphabetically by age and place. You can also search his family tree and see where he lived. He was active in many organizations. He was well known for his generosity and generosity.

Steve Boster was born in Joliet, IL, and passed away on June 6, 2022, in Madison, WI, after a long battle with COVID-19. He was the father of Donald, Sr., David Boster, and Nina Mae Hall. His surviving family includes two daughters, Natosha Peck and Crystal Boster, six grandchildren, and four brothers, Jack Boster and Sandra Blanton. A sister, Lisa Milton, as well as several nieces, nephews, are also survivors.