Melanocortin receptor 3 Antibodies

AND MC3R ELISA kits, Melanocortin receptor 3 Proteins

Many biological assays use antibodies to detect Melanocortin receptor 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Melanocortin receptor 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Melanocortin receptor 3 antibodies...

We validate the specificity of these antibodies to Melanocortin receptor 3 by testing them on tissues known to express MC3R positively and negatively. Browse below to find the MC3R antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MC3R Infographic by Boster Bio

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Anti-MC3 Receptor/MC3R Antibody Picoband®

1 Q&As

Human, Mouse

$370
Cat # A02841-2
100 μg/vial

MC3R Overview

Facts about Melanocortin receptor 3.

MC3R 3D structure. Source: alphafold

Melanocortin receptor 3 (MC3R)

Receptor for MSH (alpha, beta and gamma) and ACTH.
This receptor is mediated by G proteins which activate adenylate cyclase.

Required for expression of anticipatory patterns of action and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock action in the brain. .

Gene Information

Human
Gene Name:	MC3R
Uniprot:	P41968
Entrez:	4159

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

BMIQ9; MC3; MC3R; MC3-R; melanocortin 3 receptor; melanocortin receptor 3; Melanocortin-3 R; Melanocortin3R; Melanocortin-3R; OB20; Obesity quantitative trait locus; OQTL

Molecular Weight

Mass (kDA):
36.043 kDA

Genomic Context


Human

Location:	20q13.2
Sequence:	20; NC_000020.11 (56248732..56249815)

Tissue Specificity

Brain, placental, and gut tissues.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Obesity
Nervousness
Insulin Resistance
Inflammation
Hyperinsulinism
Hypertensive Disease
Hyperphagia
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Pediatric Obesity
Obesity, Morbid
Pituitary Diseases

Dysequilibrium Syndrome
Impaired Glucose Tolerance
Inflammatory Response
Insulin Sensitivity
Pain
Cardiovascular Diseases

Interacting Proteins

MRAP

Pathways

Energy Homeostasis
Pigmentation
Feeding Behavior
Regulation Of Energy Homeostasis
Secretion
Pathogenesis
Inflammatory Response
Localization
Regulation Of Appetite
Translation
Glucose Homeostasis
Cell Proliferation
Response To Food

Immune Response
Eating Behavior
Reverse Transcription
Regulation Of Feeding Behavior
Bioluminescence
Endocytosis
Cell Adhesion

PTMs

Phosphorylation
Oxidation
Cleavage
Iodination

Carboxylation
Glycosylation
Amidation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MC3R

References

PMID: 8463333 by Gantz I., et al. Molecular cloning of a novel melanocortin receptor.

PMID: 22433616 by Tarnow P., et al. Identification of the translation start site of the human melanocortin 3 receptor.