MBNL1 Antibodies

AND MBNL1 ELISA kits, MBNL1 Proteins

Many biological assays use antibodies to detect MBNL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MBNL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MBNL1 antibodies...

We validate the specificity of these antibodies to MBNL1 by testing them on tissues known to express MBNL1 positively and negatively. Browse below to find the MBNL1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MBNL1 Infographic by Boster Bio

All MBNL1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Muscleblind Like Protein 1 Monoclonal Antibody

5 Q&As

Human

IF, IHC, WB

$299
Cat # M02309
100ul

Anti-MBNL1 Antibody Picoband®

1 Citations

Human, Monkey, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A02309-1
100 μg/vial

Anti-Muscleblind-like protein 1 MBNL1 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02309
100ul

MBNL1 (NM_207295) Human Recombinant Protein

$1062
Cat # PROTQ9NR56
20 µg

Anti-MBNL1 Rabbit Monoclonal Antibody

Human, Mouse

$370
Cat # M02309-1
100 μl/vial

MBNL1 (NM_021038) Human Over-expression Lysate

Human

$628
Cat # LS004154
100 µg

MBNL1 Overview

Facts about Muscleblind-like protein 1.

MBNL1 3D structure. Source: alphafold

Muscleblind-like protein 1 (MBNL1)

Mediates pre-mRNA alternative splicing regulation. Acts equally as activator or repressor of splicing on particular pre-mRNA targets.

Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins.

Gene Information

Human
Gene Name:	MBNL1
Uniprot:	Q9NR56
Entrez:	4154

Family

Belongs to:

muscleblind family

Alternative Names

DKFZp686P06174; EXP40; EXP42; EXPKIAA0428EXP35; MBNL; muscleblind (Drosophila)-like; muscleblind-like (Drosophila); muscleblind-like protein 1; Triplet-expansion RNA-binding protein

Molecular Weight

Mass (kDA):
41.817 kDA

Genomic Context


Human

Location:	3q25.1-q25.2
Sequence:	3; NC_000003.12 (152243632..152465780)

Tissue Specificity

Highly expressed in cardiac, skeletal muscle and during myoblast differentiation. Weakly expressed in other tissues (at protein level). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasmic granule. Localized with DDX1, TIAL1 and YBX1 in stress granules upon stress (PubMed:18335541). Localized in the cytoplasm of multinucleated myotubes (PubMed:18335541). Colocalizes with nuclear foci of retained expanded-repeat transcripts in myotubes from patients affected by myotonic dystrophy (PubMed:10970838, PubMed:11590133, PubMed:11929853).