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- Table of Contents
1 Citations 17 Q&As
Facts about Protein max.
The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3'Lys-9' histone methyltransferase activity.
Human | |
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Gene Name: | MAX |
Uniprot: | P61244 |
Entrez: | 4149 |
Belongs to: |
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MAX family |
BHLHD4; bHLHd4MGC11225; bHLHd5; bHLHd6; bHLHd7; bHLHd8; Class D basic helix-loop-helix protein 4; helix-loop-helix zipper protein; MAX protein; Max; MGC10775; MGC18164; MGC34679; MGC36767; MYC associated factor X; Myc-associated factor X; orf1; protein max
Mass (kDA):
18.275 kDA
Human | |
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Location: | 14q23.3 |
Sequence: | 14; NC_000014.9 (65006101..65102695, complement) |
High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Nucleus. Cell projection, dendrite.
PMID: 2006410 by Blackwood E.M., et al. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.
PMID: 8426752 by Vaestrik I., et al. Alternative mRNA forms and open reading frames of the max gene.
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