Matrin-3 Antibodies

AND MATR3 ELISA kits, Matrin-3 Proteins

Many biological assays use antibodies to detect Matrin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Matrin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Matrin-3 antibodies...

We validate the specificity of these antibodies to Matrin-3 by testing them on tissues known to express MATR3 positively and negatively. Browse below to find the MATR3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MATR3 Infographic by Boster Bio

All MATR3 Products

Product

Figures

Specificity

Applications

Price

Anti-Matrin-3 MATR3 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02931
100ul

Anti-Matrin 3 MATR3 Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$405
Cat # A02931-1
100ul

Anti-Matrin 3 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02931-1
100 μl/vial

Matrin 3 (MATR3) (NM_199189) Human Over-expression Lysate

Human

$628
Cat # LS009782
100 µg

Anti-MATR3 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02931-2
100 µg/vial

MATR3 Overview

Facts about Matrin-3.

MATR3 3D structure. Source: alphafold

Matrin-3 (MATR3)

May play a role in transcription or may interact with other nuclear matrix proteins to form the inner fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.

Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728). May bind to particular miRNA hairpins (PubMed:28431233).

Gene Information

Human
Gene Name:	MATR3
Uniprot:	P43243
Entrez:	9782

Family

Belongs to:

No superfamily

Alternative Names

distal 2; DKFZp686K0542; DKFZp686K23100; matrin 3; matrin-3; vocal cord and pharyngeal weakness with distal myopathy

Molecular Weight

Mass (kDA):
94.623 kDA

Genomic Context


Human

Location:	5q31.2
Sequence:	5; NC_000005.10 (139273752..139331677)

Subcellular Localizations

Nucleus matrix.

Diseases

Hiv Infections
Myopathy
Malignant Neoplasms
Weakness
Carcinoma
Immunologic Deficiency Syndromes
Distal Muscular Dystrophies
Pseudorabies
Colonic Neoplasms
Malignant Tumor Of Colon
Tumors Of Adrenal Cortex
Malignant Neoplasm Of Adrenal Cortex

Dysplasia
Diastrophic Dysplasia
Lymphoma
Precancerous Conditions
Multiple Epiphyseal Dysplasia
Cushing Syndrome
Acidosis

Interacting Proteins

HNRNPK
HTR7
NR4A1
RASD1

Pathways

Cell Cycle
Cell Proliferation
Localization
Transport
Response To Drug
Nuclear Export
Cytoskeleton Organization
Response To 5-fluorouracil
Translation
Viral Transcription
Mrna Stabilization
S Phase
Chromatin Organization

Cell Growth
Rna Processing
Iron-sulfur Cluster Assembly
Pathogenesis
Rna Interference
Chromatin Remodeling
Nuclear Import

PTMs

Phosphorylation

Cleavage

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MATR3

References

PMID: 2033075 by Belgrader P., et al. Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix contains an extensive acidic domain.

PMID: 11525732 by Zhang Z., et al. The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs.