MARCKS Antibodies

AND MARCKS ELISA kits, MARCKS Proteins

Many biological assays use antibodies to detect MARCKS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MARCKS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MARCKS antibodies...

We validate the specificity of these antibodies to MARCKS by testing them on tissues known to express MARCKS positively and negatively. Browse below to find the MARCKS antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MARCKS Infographic by Boster Bio

All MARCKS Products

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Product

Figures

Specificity

Applications

Price

Anti-MARCKS (Ab-158) Antibody

13 Q&As

Human, Mouse, Rat

IF, WB

$360
Cat # A04133-2
100 µl

MARCKS Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1351
1 kit, containing one 96-well plate and all necessary reagents

MARCKS (Phospho-Ser158) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2453
1 kit, containing two 96-well plates and all necessary reagents

Anti-MARCKS (R157) Antibody

Human, Mouse, Rat

IHC

$405
Cat # A04133
100ul

Anti-MARCKS (phospho-S163) Antibody

Human, Mouse, Rat

IHC, WB

$482
Cat # A04133S163
100ul

Anti-Phospho-MARCKS (S158) Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04133S158
100ul

MARCKS Overview

Facts about Myristoylated alanine-rich C-kinase substrate.

MARCKS 3D structure. Source: alphafold

Myristoylated alanine-rich C-kinase substrate (MARCKS)

MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin.

MARCKS is a filamentous (F) actin cross-linking protein. .

Gene Information

Human
Gene Name:	MARCKS
Uniprot:	P29966
Entrez:	4082

Family

Belongs to:

MARCKS family

Alternative Names

80K-L protein; 80K-L; FLJ14368; MACS; MACSmyristoylated alanine-rich C-kinase substrate; MARCKS; MRACKS; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); myristoylated alanine-rich protein kinase C substrate; phosphomyristin; PKCSLFLJ90045; PRKCSL; Protein kinase C substrate, 80 kDa protein, light chain

Molecular Weight

Mass (kDA):
31.555 kDA

Genomic Context


Human

Location:	6q21
Sequence:	6; NC_000006.12 (113857345..113863475)

Subcellular Localizations

Cytoplasm, cytoskeleton. Membrane; Lipid-anchor.

Diseases

Tissue Adhesions
Neoplasms
Nervousness
Malignant Neoplasms
Neuroblastoma
Inflammation
Cell Transformation, Neoplastic
Asthma
Bipolar Disorder
Glioma
Alzheimer's Disease
Neoplasm Metastasis
Lung Diseases

Melanoma
Carcinoma
Chronic Obstructive Airway Disease
Leukemia
Hyperplasia
Lung Diseases, Obstructive
Fibrosis

Pathways

Secretion
Exocytosis
Protein Phosphorylation
Localization
Cell Proliferation
Cell Migration
Cell Adhesion
Cell Growth
Cell Motility
Transport
Cell Cycle
Cell Differentiation
Phagocytosis

Pathogenesis
Brain Development
Proteolysis
Cell Death
Translation
Regeneration
Chemotaxis

PTMs

Phosphorylation
Myristoylation
Cleavage
Dephosphorylation
Ribosylation
Acylation

Palmitoylation
Phosphorothioation
Glycosylation
Methylation
Prenylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MARCKS

References

PMID: 1860846 by Harlan D.M., et al. The human myristoylated alanine-rich C kinase substrate (MARCKS) gene (MACS). Analysis of its gene product, promoter, and chromosomal localization.

PMID: 1427823 by Sakai K., et al. Molecular cloning and chromosomal mapping of a cDNA encoding human 80K-L protein: major substrate for protein kinase C.