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MAPRE3 Antibodies
AND MAPRE3 ELISA kits, MAPRE3 Proteins
Many biological assays use antibodies to detect MAPRE3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAPRE3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAPRE3 antibodies...
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MAPRE3 Infographic by Boster Bio
All MAPRE3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M05782-1
100 μl/vial
Cat # M05782-1
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A05782-2
100 µg/vial
Cat # A05782-2
100 µg/vial
MAPRE3 Overview
Facts about Microtubule-associated protein RP/EB family member 3.
Microtubule-associated protein RP/EB family member 3 (MAPRE3)
Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and modulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth.
May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:28814570).
Gene Information
| Human | |
|---|---|
| Gene Name: | MAPRE3 |
| Uniprot: | Q9UPY8 |
| Entrez: | 22924 |
Family
| Belongs to: |
|---|
| MAPRE family |
Alternative Names
EB1 protein family member 3; EB3EBF3-S; End-binding protein 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3EBF3APC binding protein
Molecular Weight
Mass (kDA):
31.982 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p23.3 |
| Sequence: | 2; NC_000002.12 (26970637..27027219) |
Tissue Specificity
Predominantly expressed in brain and muscle.
Subcellular Localizations
Cytoplasm, cytoskeleton. Associated with the microtubule network. Detected at the plus end of microtubules.
Diseases
- Neoplasms
- Malignant Neoplasms
- Head And Neck Carcinoma
- Carcinoma
- Head And Neck Neoplasms
- Malignant Squamous Cell Neoplasm
- Adenomatous Polyposis Coli
- Polyposis
- Spastic Paraplegia, Hereditary
- Paraplegia
- Cell Transformation, Neoplastic
- Spastic Paraplegia
Interacting Proteins
- APC2
- APPL2
- DCTN2
- EIF4E2
- JUN
- LMO2
- Map1b
- MAPRE1
- MAPRE2
- MAPT
Pathways
- Dna Methylation
- Methylation
- Cell Cycle
- Transport
- Mitosis
- Chromosome Segregation
- Localization
- Pathogenesis
- Rna Interference
- Intracellular Transport
- Cell Proliferation
- G2 Phase
- Microtubule Severing
PTMs
- Methylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAPRE3
bosterbio.com/bosterbio-gene-info-cards/MAPRE3
References
PMID: 10644998 by Nakagawa H., et al. EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue.
PMID: 11161807 by Su L.-K., et al. Characterization of human MAPRE genes and their proteins.