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MAPK6 Antibodies
AND MAPK6 ELISA kits, MAPK6 Proteins
Many biological assays use antibodies to detect MAPK6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAPK6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAPK6 antibodies...
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MAPK6 Infographic by Boster Bio
All MAPK6 Products
Product
Figures
Specificity
Applications
Price
Anti-MAPK6 Antibody Picoband®
1 Citations 3 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9666
100 μg/vial
Cat # PB9666
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1200
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1200
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2256
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2256
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A03011S189-1
100ul
Cat # A03011S189-1
100ul
Human, Mouse, Rat
IHC, WB
$523
Cat # M03011-1
100 µl
Cat # M03011-1
100 µl
Human, Mouse, Rat
IF, WB
$523
Cat # M03011-2
100 µl
Cat # M03011-2
100 µl
MAPK6 Overview
Facts about Mitogen-activated protein kinase 6.
Mitogen-activated protein kinase 6 (MAPK6)
Atypical MAPK protein.
Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5.The precise role of the complex formed with MAPKAPK5 is still unclear, but the complicated follows a complicated set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | MAPK6 |
| Uniprot: | Q16659 |
| Entrez: | 5597 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
DKFZp686F03189; EC 2.7.11; EC 2.7.11.24; ERK3; ERK-3; ERK3p97-MAPK; Extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; HsT17250; MAP kinase 6; MAP kinase isoform p97; MAPK 6; MAPK6; mitogen-activated protein kinase 6; p97MAPK; PRKM6; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6
Molecular Weight
Mass (kDA):
82.681 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q21.2 |
| Sequence: | 15; NC_000015.10 (52019219..52067375) |
Tissue Specificity
Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
Subcellular Localizations
Cytoplasm. Nucleus. Translocates to the cytoplasm following interaction with MAPKAPK5.
Diseases
- Malignant Neoplasms
- Neoplasms
- Tissue Adhesions
- Adenoma
- Testicular Hypogonadism
- Peripheral Nerve Injuries
- Melanoma
- Malignant Neoplasm Of Breast
- Inflammatory Bowel Diseases
- Stinging Sensation
- Hepatitis B
- Neoplasm Invasiveness
- Sarcoma
Interacting Proteins
- EGLN3
- MAPKAPK5
Pathways
- Cell Cycle
- Cell Proliferation
- Localization
- Cell Adhesion
- Translation
- Mitosis
- Pathogenesis
- Cell Migration
- Gluconeogenesis
- Superoxide Anion Generation
- Cell Cycle Arrest
- Inflammatory Response
- Cytoskeleton Organization
PTMs
- Phosphorylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAPK6
bosterbio.com/bosterbio-gene-info-cards/MAPK6
References
PMID: 7969157 by Zhu A.X., et al. Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3.
PMID: 8875998 by Meloche S., et al. Primary structure, expression and chromosomal locus of a human homolog of rat ERK3.
1 Publications of Boster MAPK6 Antibodies & ELISA Kits
- PubMed ID: -, Chumyam A. and Saengnil,K. 2021.Transient H2O2 induction by ClO2 fumigation alte...
*More publications can be found for each product on its corresponding product page