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- Table of Contents
6 Citations 17 Q&As
6 Citations 5 Q&As
4 Citations 16 Q&As
2 Citations 16 Q&As
1 Citations 16 Q&As
4 Citations
Facts about Mitogen-activated protein kinase 14.
Accordingly, p38 MAPKs phosphorylate a wide assortment of proteins and it has been estimated that they might have approximately 200 to 300 substrates each. A few of the targets are downstream kinases that are activated through phosphorylation and additional phosphorylate additional targets.
Human | |
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Gene Name: | MAPK14 |
Uniprot: | Q16539 |
Entrez: | 1432 |
Belongs to: |
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protein kinase superfamily |
MAPK14; p38 alpha; SAPK2a
Mass (kDA):
41.293 kDA
Human | |
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Location: | 6p21.31 |
Sequence: | 6; NC_000006.12 (36027677..36122964) |
Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney.
Cytoplasm. Nucleus.
PMID: 7997261 by Lee J.C., et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis.
PMID: 7696354 by Han J., et al. Molecular cloning of human p38 MAP kinase.
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