Beta-mannosidase Antibodies

AND MANBA ELISA kits, Beta-mannosidase Proteins

Many biological assays use antibodies to detect Beta-mannosidase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Beta-mannosidase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Beta-mannosidase antibodies...

We validate the specificity of these antibodies to Beta-mannosidase by testing them on tissues known to express MANBA positively and negatively. Browse below to find the MANBA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MANBA Infographic by Boster Bio

All MANBA Products

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Product

Figures

Specificity

Applications

Price

Anti-Beta-mannosidase MANBA Antibody

Human, Mouse

IHC, WB

$405
Cat # A12748
100ul

MANBA (NM_005908) Human Over-expression Lysate

Human

$628
Cat # LS004126
100 µg

MANBA Overview

Facts about Beta-mannosidase.

MANBA 3D structure. Source: alphafold

Beta-mannosidase (MANBA)

Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of N-linked glycoprotein oligosaccharides. .

Gene Information

Human
Gene Name:	MANBA
Uniprot:	O00462
Entrez:	4126

Family

Belongs to:

glycosyl hydrolase 2 family

Alternative Names

beta-mannosidase; EC 3.2.1.25; Lysosomal beta A mannosidase; MANB1mannanase; Mannanase; mannase; mannosidase, beta A, lysosomal

Molecular Weight

Mass (kDA):
100.895 kDA

Genomic Context


Human

Location:	4q24
Sequence:	4; NC_000004.12 (102630770..102760968, complement)

Subcellular Localizations

Lysosome.

Diseases

Beta-mannosidosis
Brucella Abortus Infection
Brucella Melitensis Infection
Angiokeratoma
Brucellosis
Polyneuropathy
Melanoma
Ataxia
Leukoencephalopathies
Congenital Anomaly Of Face
Dementia, Vascular

Lysosomal Storage Diseases
Malignant Neoplasms
Neoplasms
Nervousness
Colorectal Cancer
Muscle Spasticity

Pathways

Cytokine Production
Translation
Cell Death
Necrotic Cell Death
Secretion
Macrophage Activation

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MANBA

References

PMID: 9384606 by Alkhayat A.H., et al. Human beta-mannosidase cDNA characterization and first identification of a mutation associated with human beta-mannosidosis.

PMID: 12890191 by Uchino Y., et al. Morphological and biochemical studies of human beta-mannosidosis: identification of a novel beta-mannosidase gene mutation.