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- Table of Contents
Facts about Transcription factor MafA.
Binds the insulin enhancer C1/RIPE3b element (PubMed:15665000). Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence (By similarity).
Rat | |
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Gene Name: | Mafa |
Uniprot: | D3ZNT6 |
Entrez: | 366949 |
Belongs to: |
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bZIP family |
hMafA; Pancreatic beta-cell-specific transcriptional activator; RIPE3b1; transcription factor MafA; Transcription factor RIPE3b1; v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian); V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
Mass (kDA):
37.78 kDA
Rat | |
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Location: | 7q34 |
Sequence: | 7; |
PMID: 15665000 by Zhao L., et al. The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription.
PMID: 18042454 by Rocques N., et al. GSK-3-mediated phosphorylation enhances Maf-transforming activity.