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LYPLA1 Antibodies
AND LYPLA1 ELISA kits, LYPLA1 Proteins
Many biological assays use antibodies to detect LYPLA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LYPLA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LYPLA1 antibodies...
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LYPLA1 Infographic by Boster Bio
All LYPLA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M07249-1
100 μl/vial
Cat # M07249-1
100 μl/vial
Human
$628
Cat # LS010434
100 µg
Cat # LS010434
100 µg
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A07249-2
100 µg/vial
Cat # A07249-2
100 µg/vial
LYPLA1 Overview
Facts about Acyl-protein thioesterase 1.
Acyl-protein thioesterase 1 (LYPLA1)
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins like trimeric G alpha proteins or HRAS. Has depalmitoylating action toward KCNMA1.
Has low lysophospholipase activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LYPLA1 |
| Uniprot: | O75608 |
| Entrez: | 10434 |
Family
| Belongs to: |
|---|
| AB hydrolase superfamily |
Alternative Names
acyl-protein thioesterase-1; APT1; APT-1; EC 3.1.2; EC 3.1.2.-; hAPT1; LPL1acyl-protein thioesterase 1; LPL-I; Lysophospholipase 1; lysophospholipase ILYSOPLA; lysophospholipid-specific lysophospholipase; LysoPLA I
Molecular Weight
Mass (kDA):
24.67 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q11.23 |
| Sequence: | 8; NC_000008.11 (54046367..54102017, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Bladder Neoplasm
- Influenza
- Malignant Neoplasm Of Prostate
- Neoplasm Metastasis
- Thrombus
- Fowlpox
- Stomatitis
- Reticuloendothelial Hyperplasia
- Physiological Stress
- Vesicular Stomatitis
- Carcinoma
- Tumor Suppressor Gene Inactivation Process
Pathways
- Localization
- Protein Palmitoylation
- Transport
- Dna Hypermethylation
- Dna Methylation
- Platelet Activation
- Prenylation
- Platelet Aggregation
- Dendritic Spine Morphogenesis
- Methylation
- Protein Deacylation
- Gastric Motility
PTMs
- Palmitoylation
- Depalmitoylation
- Acylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LYPLA1
bosterbio.com/bosterbio-gene-info-cards/LYPLA1
References
PMID: 11080636 by Devedjiev Y., et al. Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A.
PMID: 20418879 by Dekker F.J., et al. Small-molecule inhibition of APT1 affects Ras localization and signaling.