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- Table of Contents
5 Citations 13 Q&As
10 Citations 13 Q&As
Facts about Lipopolysaccharide-binding protein.
Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359).
Human | |
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Gene Name: | LBP |
Uniprot: | P18428 |
Entrez: | 3929 |
Belongs to: |
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BPI/LBP/Plunc superfamily |
LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; LPS-binding protein; MGC22233
Mass (kDA):
53.384 kDA
Human | |
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Location: | 20q11.23 |
Sequence: | 20; NC_000020.11 (38346482..38377013) |
Detected in blood serum (at protein level).
Secreted. Cytoplasmic granule membrane. Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
PMID: 2402637 by Schumann R.R., et al. Structure and function of lipopolysaccharide binding protein.
PMID: 7517398 by Wilde C.G., et al. Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS- mediated cell activation.
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