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- Table of Contents
Facts about Laminin subunit alpha-3.
Human | |
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Gene Name: | LAMA3 |
Uniprot: | Q16787 |
Entrez: | 3909 |
Belongs to: |
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No superfamily |
Epiligrin; LAMA3; Laminin alpha 3; Laminin5; Laminin-5
Mass (kDA):
366.649 kDA
Human | |
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Location: | 18q11.2 |
Sequence: | 18; NC_000018.10 (23689443..23956222) |
Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS.
Secreted, extracellular space, extracellular matrix, basement membrane. Major component.
PMID: 12915477 by McLean W.H.I., et al. An unusual N-terminal deletion of the laminin alpha3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome.
PMID: 15044476 by Kariya Y., et al. Characterization of laminin 5B and NH2-terminal proteolytic fragment of its alpha3B chain: promotion of cellular adhesion, migration, and proliferation.