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Lymphocyte antigen 86 Antibodies

AND LY86 ELISA kits, Lymphocyte antigen 86 Proteins

Many biological assays use antibodies to detect Lymphocyte antigen 86, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lymphocyte antigen 86 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lymphocyte antigen 86 antibodies...

We validate the specificity of these antibodies to Lymphocyte antigen 86 by testing them on tissues known to express LY86 positively and negatively. Browse below to find the LY86 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LY86 Infographic by Boster Bio

LY86 protein infographic

All LY86 Products

Product

Figures

Specificity

Applications

Price

Anti-MD-1 LY86 Antibody

Human

ELISA, IHC-P, WB

$449
Cat # A07328
0.1 mg

Anti-MD-1 LY86 Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A07328-1
0.1 mg

MD1 (LY86) (NM_004271) Human Recombinant Protein

$1249
Cat # PROTO95711
20 µg

MD1 (LY86) (NM_004271) Human Over-expression Lysate

Human

$628
Cat # LS009450
100 µg

LY86 Overview

Facts about Lymphocyte antigen 86.

LY86 3D structure

LY86 3D structure. Source: alphafold

Lymphocyte antigen 86 (LY86)

May collaborate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).

. .

Gene Information

Human
Gene Name:	LY86
Uniprot:	O95711
Entrez:	9450

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

LY86; Ly-86; lymphocyte antigen 86; MD1; MD-1; MMD-1; Protein MD-1; RP105-associated

Molecular Weight

Mass (kDA):
17.906 kDA

Molecular Weight

Genomic Context


Human

Location:	6p25.1
Sequence:	6; NC_000006.12 (6588639..6654982)

Tissue Specificity

Highly expressed in B-cells, monocytes and tonsil.

Subcellular Localizations

Secreted, extracellular space. Associated with CD180 at the cell surface.

Subcellular Localization

Diseases

Inflammation
Neoplasms
Malignant Neoplasms
Dysequilibrium Syndrome
Mucositis
Autoimmune Diseases
Crohn Disease
Decreased Immunologic Activity [pe]
Innate Immune Response
Asthma
Allergy
Colitis

Autoimmune Reaction
Autoimmunity
Cholangiocarcinoma
Drug-induced Liver Injury
Low Set Ears
Trinucleotide Repeat Expansion

Disease

Interacting Proteins

CD180

Interacting Proteins

Pathways

Cytokine Production
Immune Response
Cell Activation
Plasma Cell Differentiation
Cell Differentiation
Response To Lipopolysaccharide
Cell Proliferation
Regulation Of Cell Activation
Response To Lipid
T Cell Activation
Regulation Of Gene Expression
Inflammatory Response
Macrophage Differentiation

Flight
Reverse Transcription
Sensitization
Phagocytosis
Translation
Innate Immune Response
Mating

Pathways

PTMs

Disulfide bond

Glycoprotein

Research Areas

Apoptosis

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LY86

References

PMID: 9763566 by Miura Y., et al. RP105 is associated with MD-1 and transmits an activation signal in human B cells.

PMID: 10079183 by Begum N.A., et al. Human MD-1 homologue is a BCG-regulated gene product in monocytes: Its identification by differential display.