Lymphocyte antigen 6E Antibodies

AND LY6E ELISA kits, Lymphocyte antigen 6E Proteins

Many biological assays use antibodies to detect Lymphocyte antigen 6E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lymphocyte antigen 6E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lymphocyte antigen 6E antibodies...

We validate the specificity of these antibodies to Lymphocyte antigen 6E by testing them on tissues known to express LY6E positively and negatively. Browse below to find the LY6E antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LY6E Infographic by Boster Bio

All LY6E Products

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Price

Anti-Lymphocyte antigen 6E LY6E Antibody

3 Q&As

Human

$360
Cat # A09496-1
100 µl

Anti-LY6E/SCA-2 Antibody Picoband®

1 Q&As

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A09496-2
100 μg/vial

LY6E Overview

Facts about Lymphocyte antigen 6E.

LY6E 3D structure. Source: alphafold

Lymphocyte antigen 6E (LY6E)

Involved in T-cell development.
Believed to serve as a modulator of nicotinic acetylcholine receptors (nAChRs) activity.

In vitro inhibits alpha-3:beta-4-containing nAChRs maximum reaction. .

Gene Information

Human
Gene Name:	LY6E
Uniprot:	Q16553
Entrez:	4061

Family

Belongs to:

No superfamily

Alternative Names

Ly6E; Ly-6E; lymphocyte antigen 6 complex, locus E; Retinoic acid-induced gene E protein; RIGE; RIGE9804; RIG-Ely-6E; SCA2; SCA2Ly-6E; SCA-2lymphocyte antigen 6E; Stem cell antigen 2; Thymic shared antigen 1; TSA1; TSA-1retinoic acid induced gene E

Molecular Weight

Mass (kDA):
13.507 kDA

Genomic Context


Human

Location:	8q24.3
Sequence:	8; NC_000008.11 (143018485..143022410)

Tissue Specificity

Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

Diseases

Lupus Erythematosus, Systemic
Neoplasms
Malignant Neoplasms
Kidney Diseases
Rheumatism
Immunologic Deficiency Syndromes
Poultry Diseases
Rheumatoid Arthritis
T-cell Lymphoma
Arthritis
Lung Neoplasms
Proteinuria Of Undiagnosed Cause

Radiation Injury
Paramyxoviridae Infections
Sclerosis
Neoplasm Metastasis
Chikungunya Virus Infection
Metastatic Malignant Neoplasm To The Lung
Malignant Neoplasm Of Breast

Pathways

Pathogenesis
Acrosome Reaction
Cell Adhesion
Cell Activation
Fertilization
Metaphase
B Cell Activation
Localization
Regulation Of Type I Interferon Production
Type I Interferon Production
Disease Resistance

T Cell Differentiation
Translation
Cell Differentiation
Angiogenesis
Rna Interference
Glycolysis

PTMs

Carboxylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LY6E

References

PMID: 8650192 by Mao M., et al. RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.

PMID: 8757598 by Capone M.C., et al. Identification through bioinformatics of cDNAs encoding human thymic shared Ag-1/stem cell Ag-2: a new member of the human Ly-6 family.