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- Table of Contents
Facts about Tumor necrosis factor receptor superfamily member 3.
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT.
Promotes apoptosis via TRAF3 and TRAF5.May play a role in the development of lymphoid organs. .
Human | |
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Gene Name: | LTBR |
Uniprot: | P36941 |
Entrez: | 4055 |
Belongs to: |
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No superfamily |
CD18; D12S370; ltbetar; LT-BETA-R; LTBR; lymphotoxin B receptor; Lymphotoxin beta R; lymphotoxin beta receptor (TNFR superfamily, member 3); Lymphotoxin-beta receptor; LymphotoxinbR; TNF RIII; TNF Rrp; TNFCRTNF-RIII; TNFR superfamily, member 3; TNFR2-RP; TNFR3; TNF-R-III; TNFR-RP; TNFRSF3; TNFRSF3TNFR-III; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; Tumor necrosis factor receptor type III
Mass (kDA):
46.709 kDA
Human | |
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Location: | 12p13.31 |
Sequence: | 12; NC_000012.12 (6375160..6391571) |
Membrane; Single-pass type I membrane protein.
This article will show you how to validate the LTBR Antibody as well as the LTBR Marker. Boster Bio specializes in antibodies with high specificity and affinity. We will also talk about how this marker can be used in a variety applications. Here are a few advantages of BosterBio's antibodies and LTBR marks. We hope that you will find them useful! Here are a few examples.
The LTBR Marker in Boster Bio is a phosphoprotein that binds to an epitope that is specific to the protein known as LTab. This is the peptide that recognizes the LIGHT and LTab. Boster Bio has a proprietary ELISA platform that makes use of proprietary trade secrets to offer high-sensitivity ELISA kits. This antibody is validated by Boster across multiple platforms, using positive and negative samples. Boster is delighted to award product credits to the very first reviewer of their products.
Although the role played by the LTBR Marker in leukemia remains not known but there is evidence to suggest that this protein may have an anti-tumour effect. Lymphocytes within the tumour microenvironment activate LTbR, which is a signalling pathway. These lymphocytes also express LT. The interaction between LT-expressing leukaemic cells and stromal cell expressing LT promotes leukemogenesis. These cells can multiply and spread however their pro-leukemogenic role is removed.
Ltbr deficiency delays leukaemogenesis. The delayed development of leukaemogenesis in mice lacking Ltbr cannot be explained by the absence of lymph nodes or T-cell defects. Ltbr is essential for the production of leukaemia-inducing B-cells, which are essential for the development of leukaemia. Its absence prevents the formation of leukaemia, which is one of the major causes of death in humans.
Ltbr is a cell marker which has numerous applications in the field of biology. It is crucial to know how this marker works, as it can cause leukaemia among patients suffering from the disorder. It also affects the development and maturation of cells into precursors to hematopoietic cells. If you have any questions about the LTBR marker, please feel free to contact us. We're more than happy to address any questions you might ask and provide additional information.
Boster Bio's anti LTBR antibody was tested using WB and IHC methods using human cells. It is a synthetic peptide that corresponds to human sequences of LTBR. Boster Bio has also tested its antibodies against various known positive and negative samples. It also provides product credits to the first reviewer to submit an antibody of high-quality. Boster offers the highest-quality lysis buffers to ensure exact and precise results.
Boster Bio LTBR markers enable healthcare professionals to distinguish between active and latent TB infections. The test can help determine the risk of developing TB disease. While the LTBR marker is not utilized frequently however it is a good option for predicting the development of active TB. The LTBI protein is helpful in distinguishing latent TB disease from active TB.
LTBR antibodies are vital tools in molecular science and are suitable for various applications, including research and development in the pharmaceutical and biotechnology industries. The antibodies' versatility and sensitivity assure that target proteins can be identified and detected in a precise manner. LTBR antibodies have high affinity and specificity, and therefore they are excellent for routine lab use. Boster offers a wealth of technical resources, such as blogs, disease information , and digital tools that are accessible on the internet. Boster also provides quality lysis buffers that can help reduce cross-linking.
Boster Bio has rigorously tested all antibodies for accuracy, quality and consistency, and accuracy. They have been validated using immunohistochemistry, Western blotting, and ELISA to ensure they are effective and safe for use in research. Boster Bio also provides an array of other primary antibodies and other reagents. Below are the most important advantages of Boster Bio LTBR Antibody Validation.
Bostern Bio Antibodies have many benefits from using LTBR Marker. They vary from IHC to WB and are compatible with a wide range of cell lines and tissues. Boster provides comprehensive technical resources, such as blogs and information about diseases. The high-quality lysis buffers guarantee that the results are precise, while reducing the intensity of cross-linking.
PMID: 8486360 by Baens M., et al. Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid.
PMID: 8171323 by Crowe P.D., et al. A lymphotoxin-beta-specific receptor.