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- Table of Contents
Facts about Leukotriene B4 receptor 2.
The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
Human | |
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Gene Name: | LTB4R2 |
Uniprot: | Q9NPC1 |
Entrez: | 56413 |
Belongs to: |
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G-protein coupled receptor 1 family |
BLT2; BLT2LTB4 receptor JULF2; BLT2R; BLTR2; BLTR2LTB4-R2; JULF2; KPG_004; Leukotriene B4 R2; leukotriene B4 receptor 2; Leukotriene B4 receptor BLT2; Leukotriene B4R2; LTB4-R 2; LTB4R2; NOP9; Seven transmembrane receptor BLTR2
Mass (kDA):
37.942 kDA
Human | |
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Location: | 14q12 |
Sequence: | 14; NC_000014.9 (24310140..24312053) |
Widely expressed.
Cell membrane; Multi-pass membrane protein.
PMID: 10913346 by Tryselius Y., et al. Cloning and characterization of cDNA encoding a novel human leukotriene B4 receptor.
PMID: 10889186 by Kamohara M., et al. Molecular cloning and characterization of another leukotriene B4 receptor.