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Leukotriene A-4 hydrolase Antibodies
AND LTA4H ELISA kits, Leukotriene A-4 hydrolase Proteins
Many biological assays use antibodies to detect Leukotriene A-4 hydrolase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Leukotriene A-4 hydrolase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Leukotriene A-4 hydrolase antibodies...
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LTA4H Infographic by Boster Bio
All LTA4H Products
Product
Figures
Specificity
Applications
Price
SDS-PAGE
$250
Cat # PROTP09960
Starting from 4ug
Cat # PROTP09960
Starting from 4ug
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, WB
$523
Cat # M02399
100 µl
Cat # M02399
100 µl
Dog, Human, Mouse, Rat
IP, IF, IHC, WB
$523
Cat # M02399-1
100 µl
Cat # M02399-1
100 µl
Dog, Human, Monkey, Mouse, Rat
IP, IHC, WB
$523
Cat # M02399-2
100 µl
Cat # M02399-2
100 µl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02399-3
100 μl/vial
Cat # M02399-3
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A02399-1
100 µg/vial
Cat # A02399-1
100 µg/vial
LTA4H Overview
Facts about Leukotriene A-4 hydrolase.
Leukotriene A-4 hydrolase (LTA4H)
Epoxide hydrolase that catalyzes the last step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | LTA4H |
| Uniprot: | P09960 |
| Entrez: | 4048 |
Family
| Belongs to: |
|---|
| peptidase M1 family |
Alternative Names
EC 3.3.2.6; Leukotriene A(4) hydrolase; Leukotriene A4 Hydrolase; leukotriene A-4 hydrolase; LTA-4 hydrolase; LTA4; LTA4H
Molecular Weight
Mass (kDA):
69.285 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q23.1 |
| Sequence: | 12; NC_000012.12 (96000753..96043520, complement) |
Tissue Specificity
Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts.
Subcellular Localizations
Cytoplasm.
Diseases
- Inflammation
- Asthma
- Malignant Neoplasms
- Infarction
- Neoplasms
- Myocardial Infarction
- Tuberculosis
- Carcinogenesis
- Cerebrovascular Accident
- Arthritis
- Rhinorrhea
- Chronic Obstructive Airway Disease
- Cardiovascular Diseases
Interacting Proteins
- TINF2
Pathways
- Pathogenesis
- Cell Proliferation
- Inflammatory Response
- Chemotaxis
- Transport
- Smooth Muscle Contraction
- Cell Migration
- Monocyte Chemotaxis
- Immune Response
- Dna Methylation
- Muscle Contraction
- Hypersensitivity
- Localization
PTMs
- Cleavage
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LTA4H
bosterbio.com/bosterbio-gene-info-cards/LTA4H
References
PMID: 3654641 by Minami M., et al. Molecular cloning of a cDNA coding for human leukotriene A4 hydrolase. Complete primary structure of an enzyme involved in eicosanoid synthesis.
PMID: 2821541 by Funk C.D., et al. Molecular cloning and amino acid sequence of leukotriene A4 hydrolase.