LSM7 Antibodies

AND LSM7 ELISA kits, LSM7 Proteins

Many biological assays use antibodies to detect LSM7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LSM7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LSM7 antibodies...

We validate the specificity of these antibodies to LSM7 by testing them on tissues known to express LSM7 positively and negatively. Browse below to find the LSM7 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LSM7 Infographic by Boster Bio

All LSM7 Products

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Product

Figures

Specificity

Applications

Price

Anti-LSM7 Antibody Picoband®

+15

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A09236-1
100 μg/vial

LSM7 (NM_016199) Human Recombinant Protein

$813
Cat # PROTQ9UK45
20 µg

LSM7 (NM_016199) Human Over-expression Lysate

Human

$628
Cat # LS051690
100 µg

LSM7 Overview

Facts about U6 snRNA-associated Sm-like protein LSm7.

LSM7 3D structure. Source: alphafold

U6 snRNA-associated Sm-like protein LSm7 (LSM7)

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).

Gene Information

Human
Gene Name:	LSM7
Uniprot:	Q9UK45
Entrez:	51690

Family

Belongs to:

snRNP Sm proteins family

Alternative Names

LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm7; YNL147W

Molecular Weight

Mass (kDA):
11.602 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (2321521..2328630, complement)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Breast
Thyroid Nodule
Malignant Paraganglionic Neoplasm
Thyroid Neoplasm
Mammary Neoplasms
Radiation Injury
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Adenoma
Follicular Thyroid Carcinoma
Carcinoma, Papillary

Gastrointestinal Hemorrhage
Rectal Diseases
Carcinogenesis
Carcinoma
Patient Dependence On
Prostatic Neoplasms
Hemorrhage

Interacting Proteins

DDIT4L
LSM2
LSM3
LSM4
LSM5

LSM6
SNRPD3
SNRPF

Pathways

Translation
Cell Division
Mrna Splicing
Mrna Processing
Rna Processing
Oncogenesis

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LSM7

References

PMID: 10523320 by Achsel T., et al. A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

PMID: 12165861 by Conte N., et al. Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators.