LSM3 Antibodies

AND LSM3 ELISA kits, LSM3 Proteins

Many biological assays use antibodies to detect LSM3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LSM3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LSM3 antibodies...

We validate the specificity of these antibodies to LSM3 by testing them on tissues known to express LSM3 positively and negatively. Browse below to find the LSM3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LSM3 Infographic by Boster Bio

All LSM3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LSM3 Antibody

Human, Mouse

$405
Cat # A09429
100ul

LSM3 (NM_014463) Human Recombinant Protein

$813
Cat # PROTP62310
20 µg

LSM3 (NM_014463) Human Over-expression Lysate

Human

$628
Cat # LS027258
100 µg

LSM3 Overview

Facts about U6 snRNA-associated Sm-like protein LSm3.

LSM3 3D structure. Source: alphafold

U6 snRNA-associated Sm-like protein LSm3 (LSM3)

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).

Gene Information

Human
Gene Name:	LSM3
Uniprot:	P62310
Entrez:	27258

Family

Belongs to:

snRNP Sm proteins family

Alternative Names

LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae); SMX4; U6 snRNA-associated Sm-like protein LSm3; USS2; YLR438C

Molecular Weight

Mass (kDA):
11.845 kDA

Genomic Context


Human

Location:	3p25.1
Sequence:	3; NC_000003.12 (14178817..14201122)

Subcellular Localizations

Nucleus.

Diseases

Lymphatic Metastasis
Malignant Squamous Cell Neoplasm
Neoplasm Metastasis
Cell Transformation, Neoplastic
Malignant Neoplasms
Metastatic Malignant Neoplasm To The Lymph Node
Neoplasms
Uterine Cervical Neoplasm
Hypoxia

Malignant Tumor Of Cervix
Carcinoma
Carcinogenesis

Interacting Proteins

CLNS1A
KEAP1
LSM1
LSM10
LSM2

LSM5
LSM6
LSM7
LSM8
TCL1A

YBX1

Pathways

Rna Processing
Rna Modification
Mrna Processing
Oxidative Phosphorylation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LSM3

References

PMID: 10369684 by Salgado-Garrido J., et al. Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

PMID: 10523320 by Achsel T., et al. A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.