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- Table of Contents
Facts about Leucine-rich repeat flightless-interacting protein 1.
May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist likely by competing with the negative FLII regulator for MYD88-binding.
Human | |
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Gene Name: | LRRFIP1 |
Uniprot: | Q32MZ4 |
Entrez: | 9208 |
Belongs to: |
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LRRFIP family |
FLAP-1; FLIIAP1; GC-binding factor 2; GCF2; GCF-2; HUFI-1; leucine rich repeat (in FLII) interacting protein 1; leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; MGC10947; MGC119738; MGC119739; NEDD8-conjugating enzyme; TRIPTAR RNA-interacting protein
Mass (kDA):
89.253 kDA
Human | |
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Location: | 2q37.3 |
Sequence: | 2; NC_000002.12 (237627576..237781647) |
Ubiquitously expressed.
Nucleus. Cytoplasm.
PMID: 9705290 by Reed A.L., et al. Molecular cloning and characterization of a transcription regulator with homology to GC-binding factor.
PMID: 9671805 by Wilson S.A., et al. TRIP: a novel double stranded RNA binding protein which interacts with the leucine rich repeat of flightless I.