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- Table of Contents
Facts about Leucine-rich repeat-containing protein 4.
Organize the lamina/pathway-specific distinction of dendrites. Plays a important role for auditory synaptic responses.
Human | |
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Gene Name: | LRRC4 |
Uniprot: | Q9HBW1 |
Entrez: | 64101 |
Belongs to: |
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No superfamily |
BAG; Brain Tumor Associated Protein LRRC4; Brain Tumor-Associated Protein BAG; Leucine Rich Repeat Containing 4; Leucine-Rich Repeat-Containing 4; Leucine-Rich Repeat-Containing Protein 4; LRRC4; NAG14; Nasopharyngeal Carcinoma-Associated Gene 14 Protein; Netrin-G2 Ligand; NGL-2
Mass (kDA):
72.717 kDA
Human | |
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Location: | 7q32.1 |
Sequence: | 7; NC_000007.14 (128027071..128032107, complement) |
Specifically expressed in brain.
Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. LRRC4 and DLG4 are interdependent for synaptic localization.
PMID: 15967442 by Zhang Q., et al. Expression and functional characterization of LRRC4, a novel brain- specific member of the LRR superfamily.
PMID: 21946559 by Seiradake E., et al. Structural basis for cell surface patterning through NetrinG-NGL interactions.