Lrrc34 Antibodies

AND Lrrc34 ELISA kits, Lrrc34 Proteins

Many biological assays use antibodies to detect Lrrc34, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lrrc34 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lrrc34 antibodies...

We validate the specificity of these antibodies to Lrrc34 by testing them on tissues known to express Lrrc34 positively and negatively. Browse below to find the Lrrc34 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Lrrc34 Infographic by Boster Bio

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Anti-LRRC34 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A16000-1
100 µg/vial

Lrrc34 Overview

Facts about Leucine-rich repeat-containing protein 34.

Leucine-rich repeat-containing protein 34 (Lrrc34)

Highly expressed in stem cells in which it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4.

Also critical for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro.

Gene Information

Mouse
Gene Name:	Lrrc34
Uniprot:	Q9DAM1
Entrez:	71827

Family

Belongs to:

No superfamily

Alternative Names

FLJ27346; leucine rich repeat containing 34; leucine-rich repeat-containing protein 34; MGC27085

Molecular Weight

Mass (kDA):
46.635 kDA

Genomic Context


Mouse

Location:	3\|3 A3
Sequence:	3;

Tissue Specificity

Expressed in testis where it specifically localizes to germ cells (at protein level) (PubMed:24435972, PubMed:24991885). Not detected in other tissues tested (at protein level) (PubMed:24435972, PubMed:24991885). Expressed in pluripotent embryonic stem cells and multipotent adult germline stem cells (PubMed:24991885).

Pathways

Cell Differentiation
Gonad Development
Meiosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lrrc34

References

PMID: 24435972 by Chen T., et al. Expression and identification of a novel gene Spata34 in mouse spermatogenic cells.

PMID: 24991885 by Luehrig S., et al. Lrrc34, a novel nucleolar protein, interacts with npm1 and ncl and has an impact on pluripotent stem cells.