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- Table of Contents
Facts about Low-density lipoprotein receptor-related protein 1B.
Human | |
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Gene Name: | LRP1B |
Uniprot: | Q9NZR2 |
Entrez: | 53353 |
Belongs to: |
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LDLR family |
EC 1.1.1.94; EC 3.4.21.9; low density lipoprotein receptor related protein-deleted in tumor; low density lipoprotein receptor-related protein 1B; low density lipoprotein-related protein 1B (deleted in tumors); Low-density lipoprotein receptor-related protein-deleted in tumor; LRP1B; LRP-1B; LRP-deleted in tumors; LRPDIT; LRP-DIT; LRP-DITlow-density lipoprotein receptor-related protein 1B
Mass (kDA):
515.498 kDA
Human | |
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Location: | 2q22.1-q22.2 |
Sequence: | 2; NC_000002.12 (140231423..142132463, complement) |
Expressed in thyroid gland and in salivary gland, as well as in adult and fetal brain.
Membrane; Single-pass type I membrane protein.
PMID: 10766186 by Liu C.-X., et al. LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines.
PMID: 11031110 by Liu C.-X., et al. Genomic organization of a new candidate tumor suppressor gene, LRP1B.