Prolow-density lipoprotein receptor-related protein 1 (LRP1)

Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development.

Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and triggered LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors.