Lrit3 Antibodies

AND Lrit3 ELISA kits, Lrit3 Proteins

Many biological assays use antibodies to detect Lrit3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lrit3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lrit3 antibodies...

We validate the specificity of these antibodies to Lrit3 by testing them on tissues known to express Lrit3 positively and negatively. Browse below to find the Lrit3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Lrit3 Infographic by Boster Bio

All Lrit3 Products

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Anti-LRIT3 Antibody Picoband®

Human, Mouse, Rat

ELISA, IF, ICC, WB

$370
Cat # A10719-1
100 µg/vial

Lrit3 Overview

Facts about Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3.

Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (Lrit3)

Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 in dendrite tips (PubMed:25997951). May also have a function in cone synapse formation (PubMed:25997951).

Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi (By similarity). Can be a regulator of the FGFRs (By similarity).

Gene Information

Mouse
Gene Name:	Lrit3
Uniprot:	W8DXL4
Entrez:	242235

Family

Belongs to:

No superfamily

Alternative Names

CSNB1F; fibronectin type III, immunoglobulin and leucine rich repeat domains 4; FIGLER4; FLJ44691; Gm421; leucine-rich repeat, immunoglobulin-like and transmembrane domains 3; leucine-rich repeat, immunoglobulin-like domain and transmembranedomain-containing protein 3; LRIT3; MGC120618

Molecular Weight

Mass (kDA):
74.827 kDA

Genomic Context


Mouse

Location:	3\|3 G3
Sequence:	3;

Tissue Specificity

Detected in the outer plexiform layer (OPL) of the retina, where it localizes to rod and cone ON-bipolar cells (at protein level). Also detected in bipolar cell bodies in the inner retinal layer (INL) (at protein level).

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lrit3

References

PMID: 24598786 by Neuille M., et al. Lrit3 deficient mouse (nob6): a novel model of complete congenital stationary night blindness (cCSNB).

PMID: 25997951 by Neuille M., et al. LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation.