LPAR6 Antibodies

AND LPAR6 ELISA kits, LPAR6 Proteins

Many biological assays use antibodies to detect LPAR6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LPAR6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LPAR6 antibodies...

We validate the specificity of these antibodies to LPAR6 by testing them on tissues known to express LPAR6 positively and negatively. Browse below to find the LPAR6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LPAR6 Infographic by Boster Bio

All LPAR6 Products

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Anti-P2RY5/LPAR6 Antibody Picoband®

1 Citations 3 Q&As

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # A05725-1
100 μg/vial

LPAR6 Overview

Facts about Lysophosphatidic acid receptor 6.

LPAR6 3D structure. Source: alphafold

Lysophosphatidic acid receptor 6 (LPAR6)

Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation.

Important for the maintenance of hair growth and texture. .

Gene Information

Human
Gene Name:	LPAR6
Uniprot:	P43657
Entrez:	10161

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

ARWH1; G-protein coupled purinergic receptor P2Y5; LAH3; LPA receptor 6; LPA-6; LPAR6; lysophosphatidic acid receptor 6; MGC120358; Oleoyl-L-alpha-lysophosphatidic acid receptor; P2RY5; P2RY5ARWH1; P2Y purinoceptor 5; P2Y5; P2Y5RB intron encoded G-protein coupled receptor; Purinergic receptor 5; purinergic receptor P2Y, G-protein coupled, 5

Molecular Weight

Mass (kDA):
39.392 kDA

Genomic Context


Human

Location:	13q14.2
Sequence:	13; NC_000013.11 (48400897..48444669, complement)

Tissue Specificity

Expressed ubiquitously, including in skin and hair follicle cells. Detected in both Henle's and Huxley's layers of the inner root sheath of the hair follicle and in suprabasal layers of the epidermis (at protein level). Expressed at low levels in peripheral blood leukocytes.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Hypotrichosis
Hair Diseases
Wooly Hair
Adenocarcinoma
Hypotrichosis Simplex
Malignant Neoplasms
Colorectal Neoplasms
Polydactyly

Microsatellite Instability
Colorectal Cancer

Pathways

Hair Follicle Development
Pathogenesis
Cell Differentiation
Regulation Of Hair Follicle Development
Endothelial Cell Differentiation

PTMs

Disulfide bond
Glycoprotein

Lipoprotein
Palmitate

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LPAR6

References

PMID: 7902321 by Toguchida J., et al. Complete genomic sequence of the human retinoblastoma susceptibility gene.

PMID: 8889552 by Herzog H., et al. Intron 17 of the human retinoblastoma susceptibility gene encodes an actively transcribed G protein-coupled receptor gene.

1 Publications of Boster LPAR6 Antibodies & ELISA Kits

PubMed ID: 10.1016/j.bioactmat.2021.07.007, Electrochemically derived nanographene oxide activates endothelial tip cells and...

*More publications can be found for each product on its corresponding product page