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- Table of Contents
Facts about Leiomodin-1.
Human | |
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Gene Name: | LMOD1 |
Uniprot: | P29536 |
Entrez: | 25802 |
Belongs to: |
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tropomodulin family |
64 kDa autoantigen 1D; 64 kDa autoantigen 1D3,1D; 64 kDa autoantigen D1,64kD; D1; FLJ55689; leimodin 1 (smooth muscle); leiomodin 1 (smooth muscle); Leiomodin, muscle form; leiomodin-1; SM-LMOD; Smooth muscle leiomodin; thyroid and eye muscle autoantigen D1 (64kD); Thyroid-associated ophthalmopathy autoantigen
Mass (kDA):
67.03 kDA
Human | |
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Location: | 1q32.1 |
Sequence: | 1; NC_000001.11 (201896456..201946548, complement) |
Detected in lung vascular smooth muscle (at protein level) (PubMed:27144530). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle (PubMed:2026759). Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine (PubMed:11318603).
Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton. Colocalizes with actin filaments in sarcomeres.
PMID: 2026759 by Dong Q., et al. Cloning and sequencing of a novel 64-kDa autoantigen recognized by patients with autoimmune thyroid disease.
PMID: 11318603 by Conley C.A., et al. Leiomodins: larger members of the tropomodulin (Tmod) gene family.