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- Table of Contents
Facts about Endothelial lipase.
Binds heparin. .
Human | |
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Gene Name: | LIPG |
Uniprot: | Q9Y5X9 |
Entrez: | 9388 |
Belongs to: |
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AB hydrolase superfamily |
EC 3.1.1; EC 3.1.1.3; EDLendothelial lipase; ELlipoprotein lipase H; Endothelial cell-derived lipase; lipase, endothelial; PRO719
Mass (kDA):
56.795 kDA
Human | |
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Location: | 18q21.1 |
Sequence: | 18; NC_000018.10 (49560699..49599185) |
High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle.
Secreted.
PMID: 10318835 by Hirata K., et al. Cloning of a unique lipase from endothelial cells extends the lipase gene family.
PMID: 10192396 by Jaye M., et al. A novel endothelial-derived lipase that modulates HDL metabolism.