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- Table of Contents
Facts about Probable cytosolic iron-sulfur protein assembly protein CIAO1.
The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2 (PubMed:23891004).
Human | |
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Gene Name: | CIAO1 |
Uniprot: | O76071 |
Entrez: | 9391 |
Belongs to: |
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WD repeat CIA1 family |
CIA1; cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae); cytosolic iron-sulfur protein assembly 1; probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat domain 39; WD repeat-containing protein 39; WD40 protein Ciao1; WDR39cytosolic iron-sulfur protein assembly 1 homolog
Mass (kDA):
37.84 kDA
Human | |
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Location: | 2q11.2 |
Sequence: | 2; NC_000002.12 (96266159..96274173) |
Cytoplasm.
PMID: 9556563 by Johnstone R.W., et al. Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1.
PMID: 17041588 by Higa L.A., et al. CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.