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Protein lin-7 homolog B Antibodies
AND Lin7b ELISA kits, Protein lin-7 homolog B Proteins
Many biological assays use antibodies to detect Protein lin-7 homolog B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein lin-7 homolog B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein lin-7 homolog B antibodies...
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Lin7b Infographic by Boster Bio
All Lin7b Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M09113
100 µl
Cat # M09113
100 µl
Lin7b Overview
Facts about Protein lin-7 homolog B.
Protein lin-7 homolog B (Lin7b)
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors in the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the appropriate membrane domains.
The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 might have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and might function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Lin7b |
| Uniprot: | O88951 |
| Entrez: | 22342 |
Family
| Belongs to: |
|---|
| lin-7 family |
Alternative Names
hLin7B; lin-7 homolog B (C. elegans); LIN-7B; MALS-2protein lin-7 homolog B; MALS2veli-2; Mammalian lin-seven protein 2; Veli-2; VELI2hVeli2; Vertebrate lin-7 homolog 2
Molecular Weight
Mass (kDA):
22.914 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 7|7 B3 |
| Sequence: | 7; |
Tissue Specificity
Expressed in the kidney; predominantly in the vasa recta.
Diseases
- Neoplasms
- Bladder Neoplasm
- Embryonal Carcinoma
- Kyphosis Deformity Of Spine
- Malignant Paraganglionic Neoplasm
- Atrophy
- Tissue Adhesions
- Teratogenic Effect
- Carcinoma
- Mental Disorders
- Malignant Neoplasms
- Congenital Thrombocytopenia
Pathways
- Cell Adhesion
- Synaptic Vesicle Exocytosis
- Exocytosis
- Localization
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lin7b
bosterbio.com/bosterbio-gene-info-cards/Lin7b
References
PMID: 9753324 by Butz S., et al. A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.
PMID: 10341223 by Jo K., et al. Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.