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Protein lin-7 homolog C Antibodies
AND Lin7c ELISA kits, Protein lin-7 homolog C Proteins
Many biological assays use antibodies to detect Protein lin-7 homolog C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein lin-7 homolog C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein lin-7 homolog C antibodies...
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Lin7c Infographic by Boster Bio
All Lin7c Products
Product
Figures
Specificity
Applications
Price
Human, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A07929-1
100 µg/vial
Cat # A07929-1
100 µg/vial
Lin7c Overview
Facts about Protein lin-7 homolog C.
Protein lin-7 homolog C (Lin7c)
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.
The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Lin7c |
| Uniprot: | O88952 |
| Entrez: | 22343 |
Family
| Belongs to: |
|---|
| lin-7 family |
Alternative Names
FLJ11215; lin-7 homolog C (C. elegans); Lin-7C; LIN-7-C; MALS-3LIN-7 protein 3; MALS3protein lin-7 homolog C; Mammalian lin-seven protein 3; veli-3; VELI3Lin7c; Vertebrate lin-7 homolog 3
Molecular Weight
Mass (kDA):
21.834 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 2 E3|2 56.65 cM |
| Sequence: | 2; |
Tissue Specificity
Expressed in the kidney; particularly in the outer medullary collecting duct.
Diseases
- Tissue Adhesions
- Neoplasms
- Mood Disorders
- Attention Deficit Hyperactivity Disorder
- Obesity
- Amaurosis
- Neoplasm Metastasis
- Malnutrition
- Metastatic Malignant Neoplasm To The Lymph Node
- Retinal Degeneration
- Influenza In Birds
- Neoplasm Invasiveness
Pathways
- Localization
- Synaptic Transmission
- Cell-cell Adhesion
- Cell Adhesion
- Transport
- Protein Targeting
- Tube Formation
- Glycosylation
- Neurogenesis
- Virulence
- Establishment Of Epithelial Cell Polarity
- Demethylation
PTMs
- Demethylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lin7c
bosterbio.com/bosterbio-gene-info-cards/Lin7c
References
PMID: 9753324 by Butz S., et al. A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.
PMID: 10341223 by Jo K., et al. Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.