LIMA1 Antibodies

AND LIMA1 ELISA kits, LIMA1 Proteins

Many biological assays use antibodies to detect LIMA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LIMA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LIMA1 antibodies...

We validate the specificity of these antibodies to LIMA1 by testing them on tissues known to express LIMA1 positively and negatively. Browse below to find the LIMA1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LIMA1 Infographic by Boster Bio

All LIMA1 Products

Product

Figures

Specificity

Applications

Price

Anti-LIMA1 Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A05231
0.1 mg

Anti-EPLIN (LIMA1) Mouse Monoclonal Antibody [Clone ID: OTI1A3]

Human

IHC, WB

$523
Cat # M05231
100 µl

Anti-EPLIN/LIMA1 Antibody Picoband™

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05231-1
100 μg/vial

LIMA1 Overview

Facts about LIM domain and actin-binding protein 1.

LIMA1 3D structure. Source: alphafold

LIM domain and actin-binding protein 1 (LIMA1)

Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the amount and size of actin stress fibers and inhibits membrane ruffling.

Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments (PubMed:12566430).

Gene Information

Human
Gene Name:	LIMA1
Uniprot:	Q9UHB6
Entrez:	51474

Family

Belongs to:

No superfamily

Alternative Names

1110021C24Rik; Epithelial protein lost in neoplasm; EPLINepithelial protein lost in neoplasm beta; FLJ38853; LIM domain and actin binding 1; MGC131726; SREBP3LIM domain and actin-binding protein 1; sterol regulatory element binding protein 3

Molecular Weight

Mass (kDA):
85.226 kDA

Genomic Context


Human

Location:	12q13.12
Sequence:	12; NC_000012.12 (50175780..50283520, complement)

Tissue Specificity

Highly expressed in placenta, kidney, pancreas, prostate, ovary, spleen and heart. Also detected in lung, liver, brain, skeletal muscle, thymus, testis and intestine. Not detected in leukocytes. Isoform Beta expressed generally at very low levels. Isoform Alpha abundant in epithelial cells from mammary gland, prostate and in normal oral keratinocytes. Low levels in aortic endothelial cells and dermal fibroblasts. Not detectable in myocardium.

Subcellular Localizations

Cytoplasm. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cell membrane. Expressed in the brush border membrane of the small intestine and colocalizes with NPC1L1 and MYO5B (PubMed:29880681). Colocalizes with PXN at focal adhesions in mesangial cells (PubMed:24694988). Colocalizes with actin stress fibers in quiescent cells. PDGF stimulation induced disassembly of stress fibers and formation of peripheral and dorsal ruffles, where LIMA1 is relocalized (By similarity).