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- Table of Contents
1 Citations 17 Q&As
17 Citations 9 Q&As
5 Citations 9 Q&As
2 Citations 4 Q&As
1 Citations 5 Q&As
1 Citations 16 Q&As
1 Citations 8 Q&As
Facts about Galectin-1.
Inhibits CD45 protein phosphatase activity and for that reason the dephosphorylation of Lyn kinase. Powerful inducer of T-cell apoptosis.
Human | |
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Gene Name: | LGALS1 |
Uniprot: | P09382 |
Entrez: | 3956 |
Belongs to: |
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No superfamily |
14 kDa laminin-binding protein; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; BHL; DKFZp686E23103; GAL1; gal-1; Galaptin; galectin 1; Galectin1; Galectin-1; GBP; HBL; HLBP14; HPL; L-14; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; lectin, galactoside-binding, soluble, 1; LGALS1; Putative MAPK-activating protein PM12; S-Lac lectin 1
Mass (kDA):
14.716 kDA
Human | |
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Location: | 22q13.1 |
Sequence: | 22; NC_000022.11 (37675636..37679802) |
Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
Secreted, extracellular space, extracellular matrix.
PMID: 2719964 by Hirabayashi J., et al. Cloning and nucleotide sequence of a full-length cDNA for human 14 kDa beta-galactoside-binding lectin.
PMID: 2910856 by Couraud P.-O., et al. Molecular cloning, characterization, and expression of a human 14-kDa lectin.
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